| The Pathogenesis and Clinical Evaluation of Vertebral Fracture |
| 척추 골절의 발생 기전와 임상적 평가 방법 |
| 김덕윤 |
| 경희대학교 의과대학 핵의학교실 |
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| Abstract |
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Osteoporotic vertebral fractures are associated with decreased quality of life and high mortality. But many vertebral fractures are asymptomatic and they are frequently undetected and underdiagnosed by clinicians. Once an initial vertebral fracture is occurred, the risk of subsequent vertebral fracture rises sharply. Because these clinical consequences of vertebral fractures are preventable with appropriate pharmacologic intervention, early detection of vertebral fracture is quite important clinically. Conventional radiographs of the spine are usually the basic, standard technique in assessing vertebral fractures. But radiologic diagnosis of vertebral fracture requires standardization with high accuracy and clinicians can make differential diagnosis between osteoporotic vertebral fractures and other mimicking lesions. The diagnosis of vertebral fracture can be also made with DXA (dual energy X-ray absorptiometry) with VFA (vertebral fracture assessment) technique. Besides bone mass, several factors such as bone quality, intervertebral disc degeneration, prevalent fracture characteristics, trunk neuromuscular control are associated with the pathogenesis of vertebral fracture. This review provides a comprehensive understanding of the mechanism of vertebral fracture and a practical approach to the accurate diagnosis of vertebral fracture. |
| Key Words:
Osteoporosis, Vertebral fracture, Vertebral fracture |
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