Korean J Bone Metab > Volume 18(1); 2011 > Article
Korean Journal of Bone Metabolism 2011;18(1):1-8.
Bone Regeneration from Adipose Stem Cells
지방줄기세포를 이용한 골재생
임군일,이재선
동국대학교 의과대학
Abstract
Reconstruction of large bone defect poses a great challenge to an orthopedic surgeon. Recent advancement in stem cell research ushered the treatment of bone defect with tissue-engineered bone into near-possibility. While adipose stem cells (ASCs) are the most available cell sources for tissue regeneration, their low osteogenic potential is a disadvantage. Several strategies have been developed to enhance the osteogenic differentiation of ASCs. In this review, we summarized literatures and our experience on the technology to promote osteogenesis from ASCs.
Key Words: Adipose tissue, Bone regeneration, Mesenchymal stem cell, Osteogenesis
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