Korean J Bone Metab > Volume 16(2); 2009 > Article
Korean Journal of Bone Metabolism 2009;16(2):111-117.
A Case of Brown Tumors Caused by Primary Hyperparathyroidism Mimicking Bone Metastases
골전이로 의심된 원발성 부갑상샘 기능항진증에 의한 갈색종 1예
김형진,안세진,이종환,안 영,양재현,나임일,이국행1,이가희,김정민,이윤용
한국원자력의학원 원자력병원 내과, 이비인후과1
Primary hyperparathyroidism is a rare endocrine disease. The introduction of routine calcium measurement brought early detection and treatment of primary hyperparathyroidism, which led to a marked decrease in classical bone manifestations of the disease. We experienced the case of a 30-year-old women presenting as right shoulder pain and multiple osteolytic bone lesions suspicious of bone metastases. Extensive workups including bone biopsy were done. The result of biopsy at left proximal humerus mass was consistent with brown tumor. The intact parathyroid hormone level was elevated and a parathyroid mass was detected by 99mTc-sestamibi parathyroid scan and neck ultrasonography. The patient was diagnosed as primary hyperparathyroidism due to a parathyroid adenoma. After parathyroid adenomectomy, serum calcium and intact parathyroid hormone level returned to normal ranges. This report highlight the strong need to consider primary hyperparathyroidism in the initial diagnosis of multiple osteolytic bony lesions with hypercalcemia. [Korean Journal of Bone Metabolism, 16(2): 111-117, 2009]
Key Words: Brown tumor, Parathyroid adenoma, Primary hyperparathyroidism


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