Regulation of NFATc1 in Osteoclast Differentiation
Jung Ha Kim, Nacksung Kim
J Bone Metab. 2014;21(4):233-241.   Published online 2014 Nov 30     DOI: https://doi.org/10.11005/jbm.2014.21.4.233
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Enhanced osteoclastogenesis in patients with MSMD due to impaired response to IFN-γ
Miyuki Tsumura, Mizuka Miki, Yoko Mizoguchi, Osamu Hirata, Shiho Nishimura, Moe Tamaura, Reiko Kagawa, Seiichi Hayakawa, Masao Kobayashi, Satoshi Okada
Journal of Allergy and Clinical Immunology.2022; 149(1): 252.     CrossRef
Dendrobine attenuates osteoclast differentiation through modulating ROS/NFATc1/ MMP9 pathway and prevents inflammatory bone destruction
Wende Deng, Zongbao Ding, Yiyuan Wang, Binhua Zou, Jiehuang Zheng, Yanhui Tan, Qin Yang, Minhong Ke, Yan Chen, Song Wang, Xiaojuan Li
Phytomedicine.2022; 96: 153838.     CrossRef
SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species
Wenzheng Pan, Lin Zheng, Jiawei Gao, Lin Ye, Zhenzhong Chen, Shijie Liu, Bin Pan, Jiawei Fang, Hehuan Lai, Yejin Zhang, Kainai Ni, Chao Lou, Dengwei He
Biochemical Pharmacology.2022; 195: 114846.     CrossRef
Euphoesulatin A prevents osteoclast differentiation and bone loss via inhibiting RANKL-induced ROS production and NF-κB and MAPK signal pathways
Yu-ting Zhang, Chen Hu, Song-xuan Zhang, Hui-hao Zhou, Jun Xu, Jian-da Ma, Lie Dai, Qiong Gu
Bioorganic Chemistry.2022; 119: 105511.     CrossRef
Substrate stiffness regulates the differentiation profile and functions of osteoclasts via cytoskeletal arrangement
Qingxuan Wang, Jing Xie, Chenchen Zhou, Wenli Lai
Cell Proliferation.2022;[Epub]     CrossRef
2E‐Decene‐4,6‐diyn‐1‐ol‐acetate inhibits osteoclastogenesis through mitogen‐activated protein kinase‐c‐Fos‐NFATc1 signalling pathways
Young Ran Park, Xiang‐Dong Su, Saroj Kumar Shrestha, Seo Young Yang, Yunjo Soh
Clinical and Experimental Pharmacology and Physiology.2022; 49(3): 341.     CrossRef
Effects of Sparganii Rhizoma on Osteoclast Formation and Osteoblast Differentiation and on an OVX-Induced Bone Loss Model
Sungyub Lee, Minsun Kim, Sooyeon Hong, Eom Ji Kim, Jae-Hyun Kim, Youngjoo Sohn, Hyuk-Sang Jung
Frontiers in Pharmacology.2022;[Epub]     CrossRef
D(-)-salicin inhibits RANKL-induced osteoclast differentiation and function in vitro
Yu Xiao, Yansi Xian, Xinmei Hu, Zhongquan Qi
Fitoterapia.2022; 157: 104981.     CrossRef
Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the machine learning method framework cTAP
Honglin Wang, Pujan Joshi, Seung-Hyun Hong, Peter F. Maye, David W. Rowe, Dong-Guk Shin
BMC Genomics.2022;[Epub]     CrossRef
The gut microbiota can be a potential regulator and treatment target of bone metastasis
Kelly F. Contino, Hariom Yadav, Yusuke Shiozawa
Biochemical Pharmacology.2022; 197: 114916.     CrossRef
Cryptotanshinone Suppressed Postmenopausal Osteoporosis by Preventing RANKL-Mediated Osteoclastogenesis against Kidney Injury
Wenjiu Yang, Jing Han, Shuo Gong, Jun Zhao, Tengbo Yu, Jinfeng Ma, Mohd Ramli Elvy Suhana
Evidence-Based Complementary and Alternative Medicine.2022; 2022: 1.     CrossRef
Bone Health in Patients with Dyslipidemias: An Underestimated Aspect
Panagiotis Anagnostis, Matilda Florentin, Sarantis Livadas, Irene Lambrinoudaki, Dimitrios G. Goulis
International Journal of Molecular Sciences.2022; 23(3): 1639.     CrossRef
Interleukin-6 transiently promotes proliferation of osteoclast precursors and stimulates the production of inflammatory mediators
Peng-Yuan Chang, Hung-Kang Wu, Yu-Hsu Chen, Yu-Pao Hsu, Ming-Te Cheng, Ching-Hsiao Yu, Shau-Kwaun Chen
Molecular Biology Reports.2022; 49(5): 3927.     CrossRef
Biomimetic hierarchical implant surfaces promote early osseointegration in osteoporotic rats by suppressing macrophage activation and osteoclastogenesis
Xiaohan Dai, Yunyang Bai, Boon Chin Heng, Yiping Li, Zhangui Tang, Changjian Lin, Ousheng Liu, Ying He, Xuehui Zhang, Xuliang Deng
Journal of Materials Chemistry B.2022; 10(11): 1875.     CrossRef
Bone erosion in inflammatory arthritis is attenuated by Trichinella spiralis through inhibiting M1 monocyte/macrophage polarization
Yuli Cheng, Yan Yu, Qinghui Zhuang, Lei Wang, Bin Zhan, Suqin Du, Yiqi Liu, Jingjing Huang, Junfeng Hao, Xinping Zhu
iScience.2022; 25(3): 103979.     CrossRef
Chemistry, Biosynthesis and Pharmacology of Sarsasapogenin: A Potential Natural Steroid Molecule for New Drug Design, Development and Therapy
Nur Hanisah Mustafa, Mahendran Sekar, Shivkanya Fuloria, M. Yasmin Begum, Siew Hua Gan, Nur Najihah Izzati Mat Rani, Subban Ravi, Kumarappan Chidambaram, Vetriselvan Subramaniyan, Kathiresan V. Sathasivam, Srikanth Jeyabalan, Subasini Uthirapathy, Sivasan
Molecules.2022; 27(6): 2032.     CrossRef
Effects of Artemisia annua L. Essential Oil on Osteoclast Differentiation and Function Induced by RANKL
Wen Sun, Guangyue Yang, Fang Zhang, Chenguo Feng, Mingjie Liang, Pengfei Jia, Zhongliang Zhao, Hailing Guo, Yongfang Zhao, Mohamed Z. M. Salem
Evidence-Based Complementary and Alternative Medicine.2022; 2022: 1.     CrossRef
Aster saponin A2 inhibits osteoclastogenesis through mitogen-activated protein kinase-c-Fos-NFATc1 signaling pathway
Xiang-Dong Su, Seo Y Yang, Saroj K Shrestha, Yunjo Soh
Journal of Veterinary Science.2022;[Epub]     CrossRef
Auraptene ameliorates osteoporosis by inhibiting RANKL/NFATc1 pathway-mediated bone resorption based on network pharmacology and experimental evaluation
Mi H. Kim, La Y. Choi, Jae Y. Chung, Eun-Jung Kim, Woong M. Yang
Bone & Joint Research.2022; 11(5): 304.     CrossRef
Drug repositioning of polaprezinc for bone fracture healing
Eun Ae Ko, Yoo Jung Park, Dong Suk Yoon, Kyoung-Mi Lee, Jihyun Kim, Sujin Jung, Jin Woo Lee, Kwang Hwan Park
Communications Biology.2022;[Epub]     CrossRef
LY450139 Inhibited Ti-Particle-Induced Bone Dissolution via Suppressing Notch and NF-κB Signaling Pathways
Jijian Gao, Peng Wu, Yingjun Chi, Hongyu Xu, Yong Zhao, Nanyan Song, Yuanqing Mao
Calcified Tissue International.2022; 111(2): 211.     CrossRef
Roles of osteoclast-associated receptor in rheumatoid arthritis and osteoarthritis
Gyeong Min Kim, Hana Park, Soo Young Lee
Joint Bone Spine.2022; 89(5): 105400.     CrossRef
12-Deoxyphorbol-13-Hexadecanoate Abrogates OVX-Induced Bone Loss in Mice and Osteoclastogenesis via Inhibiting ROS Level and Regulating RANKL-Mediated NFATc1 Activation
Qi He, Junzheng Yang, Delong Chen, Yejia Li, Dawei Gong, Hui Ge, Zihao Wang, Haibin Wang, Peng Chen
Frontiers in Pharmacology.2022;[Epub]     CrossRef
Identification of Genes with Altered Methylation in Osteoclast Differentiation and Its Roles in Osteoporosis
Renpeng Peng, Yimin Dong, Honglei Kang, Qian Guo, Meipeng Zhu, Feng Li
DNA and Cell Biology.2022; 41(6): 575.     CrossRef
Overexpression of Neurogenin 1 Negatively Regulates Osteoclast and Osteoblast Differentiation
Jung Ha Kim, Kabsun Kim, Inyoung Kim, Semun Seong, Jeong-Tae Koh, Nacksung Kim
International Journal of Molecular Sciences.2022; 23(12): 6708.     CrossRef
Systemic Dietary Hesperidin Modulation of Osteoclastogenesis, Bone Homeostasis and Periodontal Disease in Mice
Vinícius de Paiva Gonçalves, Marta Liliana Musskopf, Angeliz Rivera-Concepcion, Christina Yu, Sing Wai Wong, Stephen A. Tuin, Yizu Jiao, Cristiano Susin, Luís Carlos Spolidorio, Patricia Almeida Miguez
International Journal of Molecular Sciences.2022; 23(13): 7100.     CrossRef
BCAT1 promotes osteoclast maturation by regulating branched-chain amino acid metabolism
Miyeon Go, Eunji Shin, Seo Young Jang, Miso Nam, Geum-Sook Hwang, Soo Young Lee
Experimental & Molecular Medicine.2022; 54(6): 825.     CrossRef
Immunology of osteoporosis: relevance of inflammatory targets for the development of novel interventions
Syed Sufian Ahmad, Faraha Ahmed, Ruhi Ali, Mohammed M Ghoneim, Sultan Alshehri, Abul Kalam Najmi, Sayeed Ahmad, Mohammad Zaki Ahmad, Javed Ahmad, Mohammad Ahmed Khan
Immunotherapy.2022; 14(10): 815.     CrossRef
Strontium Functionalized in Biomaterials for Bone Tissue Engineering: A Prominent Role in Osteoimmunomodulation
Jiaqian You, Yidi Zhang, Yanmin Zhou
Frontiers in Bioengineering and Biotechnology.2022;[Epub]     CrossRef
Urolithin B suppresses osteoclastogenesis via inhibiting RANKL‐induced signalling pathways and attenuating ROS activities
Zechao Qu, Hao An, Mingzhe Feng, Wangli Huang, Dong Wang, Zhen Zhang, Liang Yan
Journal of Cellular and Molecular Medicine.2022; 26(16): 4428.     CrossRef
(S)-Equol Is More Effective than (R)-Equol in Inhibiting Osteoclast Formation and Enhancing Osteoclast Apoptosis, and Reduces Estrogen Deficiency–Induced Bone Loss in Mice
Miori Tanaka, Shungo Fujii, Hirofumi Inoue, Nobuyuki Takahashi, Yoshiko Ishimi, Mariko Uehara
The Journal of Nutrition.2022; 152(8): 1831.     CrossRef
Mussaendoside O, a N-triterpene cycloartane saponin, attenuates RANKL-induced osteoclastogenesis and inhibits lipopolysaccharide-induced bone loss
Minju Gal, Okwha Kim, Phuong Thao Tran, Le Thanh Huong, Nguyen Xuan Nhiem, Phan Van Kiem, Nguyen Hai Dang, Jeong-Hyung Lee
Phytomedicine.2022; 105: 154378.     CrossRef
Changes in Metabolism and Mitochondrial Bioenergetics during Polyethylene-Induced Osteoclastogenesis
Nur Shukriyah Mohamad Hazir, Nor Hamdan Mohamad Yahaya, Muhamad Syahrul Fitri Zawawi, Hanafi Ahmad Damanhuri, Norazlina Mohamed, Ekram Alias
International Journal of Molecular Sciences.2022; 23(15): 8331.     CrossRef
23-Hydroxyursolic acid from Viburnum lutescens inhibits osteoclast differentiation in vitro and lipopolysaccharide-induced bone loss in vivo by suppressing c-Fos and NF-κB signalling
Le Thanh Huong, Minju Gal, Okwha Kim, Phuong Thao Tran, Nguyen Xuan Nhiem, Phan Van Kiem, Chau Van Minh, Nguyen Hai Dang, Jeong-Hyung Lee
International Immunopharmacology.2022; 111: 109038.     CrossRef
Cysteamine affects skeletal development and impairs motor behavior in zebrafish
Chao Chen, Yongliang Zheng, Xue Li, Li Zhang, Kangyu Liu, Sujie Sun, Zilin Zhong, Hongmei Hu, Fasheng Liu, Guanghua Xiong, Xinjun Liao, Huiqiang Lu, Yanlong Bi, Jianjun Chen, Zigang Cao
Frontiers in Pharmacology.2022;[Epub]     CrossRef
PI3K-activated MSC proteomes inhibit mammary tumors via Hsp90ab1 and Myh9
Xun Sun, Kexin Li, Uma K. Aryal, Bai-Yan Li, Hiroki Yokota
Molecular Therapy - Oncolytics.2022; 26: 360.     CrossRef
A Review of Signaling Transduction Mechanisms in Osteoclastogenesis Regulation by Autophagy, Inflammation, and Immunity
Xishuai Tong, Gengsheng Yu, Xiaohui Fu, Ruilong Song, Jianhong Gu, Zongping Liu
International Journal of Molecular Sciences.2022; 23(17): 9846.     CrossRef
Experimental Study on the Inhibition of RANKL-Induced Osteoclast Differentiation In Vitro by Metformin Hydrochloride
Zhang Chen, Liu Zige, Yeow Sai Kiang, Chen Desheng, Patrizia D’Amelio
International Journal of Endocrinology.2022; 2022: 1.     CrossRef
Dietary organosulfur compounds: Emerging players in the regulation of bone homeostasis by plant-derived molecules
Laura Gambari, Brunella Grigolo, Francesco Grassi
Frontiers in Endocrinology.2022;[Epub]     CrossRef
MicroRNA‐506 ameliorates breast cancer‐induced osteolytic bone metastasis via the NFATc‐1 signaling pathway
Feng Lv, Jingbo Qin, Shuxin Kong, Limin Pan, Ran Ding
Journal of Biochemical and Molecular Toxicology.2022;[Epub]     CrossRef
Anti‑osteoclastogenic effects of Coriandrum sativum L. via the NF‑κB and ERK‑mediated NFATc1 signaling pathways
Jung-Sun Sim, Hwa-Yeong Lee, Mijung Yim
Molecular Medicine Reports.2022;[Epub]     CrossRef
Context-Dependent Roles for Toll-Like Receptors 2 and 9 in the Pathogenesis of Staphylococcus aureus Osteomyelitis
Jenna R. Petronglo, Nicole E. Putnam, Caleb A. Ford, Virginia Cruz-Victorio, Jacob M. Curry, Casey E. Butrico, Laura E. Fulbright, Joshua R. Johnson, Sun H. Peck, Sana R. Fatah, James E. Cassat, Andreas J. Bäumler
Infection and Immunity.2022;[Epub]     CrossRef
Ectodysplasin A1 Deficiency Leads to Osteopetrosis-like Changes in Bones of the Skull Associated with Diminished Osteoclastic Activity
Christine Schweikl, Sigrun Maier-Wohlfart, Holm Schneider, Jung Park
International Journal of Molecular Sciences.2022; 23(20): 12189.     CrossRef
PARK2 Induces Osteoclastogenesis through Activation of the NF-κB Pathway
Seo Jin Hong, Suhan Jung, Ji Sun Jang, Shenzheng Mo, Jun-Oh Kwon, Min Kyung Kim, Hong-Hee Kim
Molecules and Cells.2022; 45(10): 749.     CrossRef
Cholesterol and fat in diet disrupt bone and tooth homeostasis in mice
Yurie Sato, Masahiro Hosonuma, Daiki Sugawara, Yuki Azetsu, Akiko Karakawa, Masahiro Chatani, Takahiro Funatsu, Masamichi Takami, Nobuhiro Sakai
Biomedicine & Pharmacotherapy.2022; 156: 113940.     CrossRef
Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase
Yihe Zhang, Bingjie Jiang, Pengyuan Zhang, Sung K. Chiu, Meng H. Lee
Bone & Joint Research.2022; 11(11): 763.     CrossRef
KBTBD11, encoding a novel PPARγ target gene, is involved in NFATc1 proteolysis by interacting with HSC70 and HSP60
Kazuhisa Watanabe, Ayumi Matsumoto, Hidetoshi Tsuda, Sadahiko Iwamoto
Scientific Reports.2022;[Epub]     CrossRef
Regulation of differentiation and generation of osteoclasts in rheumatoid arthritis
Qing Niu, Jinfang Gao, Lei Wang, Jiaxi Liu, Liyun Zhang
Frontiers in Immunology.2022;[Epub]     CrossRef
RANKL-responsive epigenetic mechanism reprograms macrophages into bone-resorbing osteoclasts
Seyeon Bae, Kibyeong Kim, Keunsoo Kang, Haemin Kim, Minjoon Lee, Brian Oh, Kaichi Kaneko, Sungkook Ma, Jae Hoon Choi, Hojoong Kwak, Eun Young Lee, Sung Ho Park, Kyung-Hyun Park-Min
Cellular & Molecular Immunology.2022; 20(1): 94.     CrossRef
Effect of Spatholobus Suberectus Extract (SSE) on RANKL-treated RAW264.7 and LPS-induced Bone Loss
Dae Joong Lee, Jong Hyun Hwang, Do Hwi Park, Ki Sung Kang, Chan Yong Jeon, Gwi Seo Hwang
The Journal of Internal Korean Medicine.2022; 43(6): 1134.     CrossRef
A Polymer-Nanoparticles Drug Delivery System Co-Delivering Artesunate and Alendronate for Local Therapy of Breast Cancer Metastatic Osteolysis
Xi Cheng, Xuefeng Zhou, Qianshu Dou, Buyun Ma, Jinrong Wei, Qi Ge, Guoqin Jiang, yunzhu qian
SSRN Electronic Journal .2022;[Epub]     CrossRef
Pharmacological evaluation of imidazole‐derived bisphosphonates on receptor activator of nuclear factor‐κB ligand‐induced osteoclast differentiation and function
Jianguo Lin, Ying Peng, Qingzhu Liu, Ke Li, Gaochao Lv, Yann Seimbille, Gang Huang, Feng Gao, Ling Qiu
Chemical Biology & Drug Design.2021; 97(1): 121.     CrossRef
Breaking the vicious cycle between tumor cell proliferation and bone resorption by chloroquine-loaded and bone-targeted polydopamine nanoparticles
Yitong Wang, Hui Chen, Kaili Lin, Ting Ying, Quan Huang, Xiaopan Cai, Jianru Xiao, Qiang Zhang, Yiyun Cheng
Science China Materials.2021; 64(2): 474.     CrossRef
Kirenol inhibits RANKL-induced osteoclastogenesis and prevents ovariectomized-induced osteoporosis via suppressing the Ca2+-NFATc1 and Cav-1 signaling pathways
Binhua Zou, Jiehuang Zheng, Wende Deng, Yanhui Tan, Ligang Jie, Yuan Qu, Qin Yang, Minhong Ke, Zongbao Ding, Yan Chen, Qinghong Yu, Xiaojuan Li
Phytomedicine.2021; 80: 153377.     CrossRef
PMSA prevents osteoclastogenesis and estrogen-dependent bone loss in mice
Eunjin Cho, Zhihao Chen, Mina Ding, Jihyoun Seong, Sunwoo Lee, Sang Hyun Min, Dong Kyu Choi, Tae-Hoon Lee
Bone.2021; 142: 115707.     CrossRef
Agrimophol suppresses RANKL-mediated osteoclastogenesis through Blimp1-Bcl6 axis and prevents inflammatory bone loss in mice
Jinjin Cao, Shaoming Wang, Congmin Wei, Hongru Lin, Chen Zhang, Yehui Gao, Zixian Xu, Zhou Cheng, Wan-chun Sun, Hong-bing Wang
International Immunopharmacology.2021; 90: 107137.     CrossRef
Dectin‐1–mediated suppression of RANKL‐induced osteoclastogenesis by glucan from baker's yeast
Shiika Hara, Yoshie Nagai‐Yoshioka, Ryota Yamasaki, Yoshiyuki Adachi, Yuko Fujita, Kouji Watanabe, Kenshi Maki, Tatsuji Nishihara, Wataru Ariyoshi
Journal of Cellular Physiology.2021; 236(7): 5098.     CrossRef
Overexpression of c‐Fos reverses osteoprotegerin‐mediated suppression of osteoclastogenesis by increasing the Beclin1‐induced autophagy
Xishuai Tong, Miaomiao Chen, Ruilong Song, Hongyan Zhao, Jianchun Bian, Jianhong Gu, Zongping Liu
Journal of Cellular and Molecular Medicine.2021; 25(2): 937.     CrossRef
Is medication-related osteonecrosis of the jaw associated with tumor necrosis factor-α inhibition?
Stacy A. Rosenberg, Cesar Migliorati, Georgios E. Romanos
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology.2021; 131(4): 422.     CrossRef
N‐[2‐(4‐benzoyl‐1‐piperazinyl)phenyl]‐2‐(4‐chlorophenoxy) acetamide is a novel inhibitor of resorptive bone loss in mice
Zhihao Chen, Eunjin Cho, Mina Ding, Jihyoun Seong, Xiangguo Che, Sunwoo Lee, Byung‐Ju Park, Je‐Yong Choi, Tae‐Hoon Lee
Journal of Cellular and Molecular Medicine.2021; 25(3): 1425.     CrossRef
Energy Metabolism and Ketogenic Diets: What about the Skeletal Health? A Narrative Review and a Prospective Vision for Planning Clinical Trials on this Issue
Daniela Merlotti, Roberta Cosso, Cristina Eller-Vainicher, Fabio Vescini, Iacopo Chiodini, Luigi Gennari, Alberto Falchetti
International Journal of Molecular Sciences.2021; 22(1): 435.     CrossRef
Serine/threonine phosphatases in osteoclastogenesis and bone resorption
Ismael Y. Karkache, Jeyaram R. Damodaran, David H.H. Molstad, Elizabeth W. Bradley
Gene.2021; 771: 145362.     CrossRef
MEF2C regulates osteoclastogenesis and pathologic bone resorption via c-FOS
Takayuki Fujii, Koichi Murata, Se-Hwan Mun, Seyeon Bae, Ye Ji Lee, Tannia Pannellini, Kyuho Kang, David Oliver, Kyung-Hyun Park-Min, Lionel B. Ivashkiv
Bone Research.2021;[Epub]     CrossRef
Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss
Wei Yu, Leilei Zhong, Lutian Yao, Yulong Wei, Tao Gui, Ziqing Li, Hyunsoo Kim, Nicholas Holdreith, Xi Jiang, Wei Tong, Nathaniel Dyment, X. Sherry Liu, Shuying Yang, Yongwon Choi, Jaimo Ahn, Ling Qin
Journal of Clinical Investigation.2021;[Epub]     CrossRef
Effects of Caffeic Acid and Its Derivatives on Bone: A Systematic Review
Sophia Ogechi Ekeuku, Kok-Lun Pang, Kok-Yong Chin
Drug Design, Development and Therapy.2021; Volume 15: 259.     CrossRef
Inhibition of zoledronic acid derivatives with extended methylene linkers on osteoclastogenesis involve downregulation of JNK and Akt pathways
Ying Peng, Qingzhu Liu, Dong Xu, Ke Li, Hang Li, Ling Qiu, Jianguo Lin
Cell Biology International.2021; 45(5): 1015.     CrossRef
2-NPPA Mitigates Osteoclastogenesis via Reducing TRAF6-Mediated c-fos Expression
Zhihao Chen, Mina Ding, Eunjin Cho, Jihyoun Seong, Sunwoo Lee, Tae-Hoon Lee
Frontiers in Pharmacology.2021;[Epub]     CrossRef
Osteosarcoma-derived exosomal miR-501-3p promotes osteoclastogenesis and aggravates bone loss
Longshuai Lin, Hongjie Wang, Weihong Guo, Enjun He, Kai Huang, Qinghua Zhao
Cellular Signalling.2021; 82: 109935.     CrossRef
Osteoclasts Differentiation from Murine RAW 264.7 Cells Stimulated by RANKL: Timing and Behavior
Nadia Lampiasi, Roberta Russo, Igor Kireev, Olga Strelkova, Oxana Zhironkina, Francesca Zito
Biology.2021; 10(2): 117.     CrossRef
Isofraxidin Inhibits Receptor Activator of Nuclear Factor-κB Ligand–Induced Osteoclastogenesis in Bone Marrow–Derived Macrophages Isolated from Sprague–Dawley Rats by Regulating NF-κB/NFATc1 and Akt/NFATc1 Signaling Pathways
Wei Wang, Bo Wang
Cell Transplantation.2021; 30: 096368972199032.     CrossRef
Undercarboxylated osteocalcin inhibits the early differentiation of osteoclast mediated by Gprc6a
Hailong Wang, Jinqiao Li, Zihan Xu, Feng Wu, Hongyu Zhang, Chao Yang, Jian Chen, Bai Ding, Xiukun Sui, Zhifeng Guo, Yinghui Li, Zhongquan Dai
PeerJ.2021; 9: e10898.     CrossRef
Bone Marrow Homeostasis Is Impaired via JAK/STAT and Glucocorticoid Signaling in Cancer Cachexia Model
Jinyeong Yu, Sanghyuk Choi, Aran Park, Jungbeom Do, Donghyun Nam, Youngjae Kim, Jinok Noh, Kil Yeon Lee, Chi Hoon Maeng, Ki-Sook Park
Cancers.2021; 13(5): 1059.     CrossRef
Eleutherococcus sessiliflorus Inhibits Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL)-Induced Osteoclast Differentiation and Prevents Ovariectomy (OVX)-Induced Bone Loss
Sang-Yong Han, June-Hyun Kim, Eun-Heui Jo, Yun-Kyung Kim
Molecules.2021; 26(7): 1886.     CrossRef
Biological Evaluation and Transcriptomic Analysis of Corylin as an Inhibitor of Osteoclast Differentiation
Anna Xiao-Dan Yu, Jian Xiao, Shi-Zheng Zhao, Xiang-Peng Kong, Kenneth Kin-Leung Kwan, Brody Zhong-Yu Zheng, Kevin Qi-Yun Wu, Tina Ting-Xia Dong, Karl Wah-Keung Tsim
International Journal of Molecular Sciences.2021; 22(7): 3540.     CrossRef
Do we use methylation of NFATC1 and FOS genes as a biomarker for postmenopausal osteoporosis?
R Kalkan, O Tosun
Balkan Journal of Medical Genetics .2021; 23(2): 35.     CrossRef
Disease progression associated with low bone mass in axial spondyloarthropathy patients
De Hao Liu, Juan Chen, Xiong Jie Zhuang, li Chun Chen
Archives of Osteoporosis.2021;[Epub]     CrossRef
TPCA‐1 negatively regulates inflammation mediated by NF‐κB pathway in mouse chronic periodontitis model
Bo Wang, Shizhu Bai, Jiang Wang, Nan Ren, Rui Xie, Geng Cheng, Yan Yu
Molecular Oral Microbiology.2021; 36(3): 192.     CrossRef
Tumor- and osteoclast-derived NRP2 in prostate cancer bone metastases
Navatha Shree Polavaram, Samikshan Dutta, Ridwan Islam, Arup K. Bag, Sohini Roy, David Poitz, Jeffrey Karnes, Lorenz C. Hofbauer, Manish Kohli, Brian A. Costello, Raffael Jimenez, Surinder K. Batra, Benjamin A. Teply, Michael H. Muders, Kaustubh Datta
Bone Research.2021;[Epub]     CrossRef
The hidden secrets of soluble RANKL in bone biology
Jeevithan Elango, Bin Bao, Wenhui Wu
Cytokine.2021; 144: 155559.     CrossRef
Role of ZBTB7A zinc finger in tumorigenesis and metastasis
Atul Kumar Singh, Shiv Verma, Prem Prakash Kushwaha, Kumari Sunita Prajapati, Mohd Shuaib, Shashank Kumar, Sanjay Gupta
Molecular Biology Reports.2021; 48(5): 4703.     CrossRef
The KDM4B–CCAR1–MED1 axis is a critical regulator of osteoclast differentiation and bone homeostasis
Sun-Ju Yi, You-Jee Jang, Hye-Jung Kim, Kyubin Lee, Hyerim Lee, Yeojin Kim, Junil Kim, Seon Young Hwang, Jin Sook Song, Hitoshi Okada, Jae-Il Park, Kyuho Kang, Kyunghwan Kim
Bone Research.2021;[Epub]     CrossRef
The estrogen-related receptor γ modulator, GSK5182, inhibits osteoclast differentiation and accelerates osteoclast apoptosis
Hyun-Ju Kim, Hye-Jin Yoon, Dong-Kyo Lee, Xian Jin, Xiangguo Che, Je-Yong Choi
BMB Reports.2021; 54(5): 266.     CrossRef
Novel Majeed Syndrome–Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis
Farzana Bhuyan, Adriana A. de Jesus, Jacob Mitchell, Evgenia Leikina, Rachel VanTries, Ronit Herzog, Karen B. Onel, Andrew Oler, Gina A. Montealegre Sanchez, Kim A. Johnson, Lena Bichell, Bernadette Marrero, Luis Fernandez De Castro, Yan Huang, Katherine
Arthritis & Rheumatology.2021; 73(6): 1021.     CrossRef
Low-Level Laser Irradiation Stimulates RANKL-Induced Osteoclastogenesis via the MAPK Pathway in RAW 264.7 Cells
Jae-Min Song, Bong-Soo Park, Sang-Hun Shin, In-Ryoung Kim
Applied Sciences.2021; 11(12): 5360.     CrossRef
6-Shogaol promotes bone resorption and accelerates orthodontic tooth movement through the JNK-NFATc1 signaling axis
Xiaofang Zhu, Hao Yuan, Ouyang Ningjuan, Carroll Ann Trotman, Thomas E. Van Dyke, Jake Jinkun Chen, Guofang Shen
Journal of Bone and Mineral Metabolism.2021; 39(6): 962.     CrossRef
JMJD3: a critical epigenetic regulator in stem cell fate
Yuanjie Ding, Yuanchun Yao, Xingmu Gong, Qi Zhuo, Jinhua Chen, Miao Tian, Maryam Farzaneh
Cell Communication and Signaling.2021;[Epub]     CrossRef
A novel role of HSP90 in regulating osteoclastogenesis by abrogating Rab11b-driven transport
Manh Tien Tran, Yuka Okusha, Yunxia Feng, Chiharu Sogawa, Takanori Eguchi, Tomoko Kadowaki, Eiko Sakai, Takayuki Tsukuba, Kuniaki Okamoto
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research.2021; 1868(10): 119096.     CrossRef
Inhibition of NFAM1 suppresses phospho‐SAPK/JNK signaling during osteoclast differentiation and bone resorption
Purushoth Ethiraj, Ishraq A. Haque, Anna K. Alford, Wenyu Gou, Toolika Singh, Yuvaraj Sambandam, Jessica D. Hathaway‐Schrader, Sakamuri V. Reddy
Journal of Cellular Biochemistry.2021; 122(10): 1534.     CrossRef
Solanum nigrum Line inhibits osteoclast differentiation and suppresses bone mineral density reduction in the ovariectomy‑induced osteoporosis model
Jae-Hyun Kim, Hwajeong Shin, Minsun Kim, Sangwoo Kim, Kwangchan Song, Hyuk-Sang Jung, Youngjoo Sohn
Molecular Medicine Reports.2021;[Epub]     CrossRef
Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis
Ilandarage Menu Neelaka Molagoda, Chang-Hee Kang, Mi-Hwa Lee, Yung Hyun Choi, Chang-Min Lee, Seungheon Lee, Gi-Young Kim
Biochemical Pharmacology.2021; 192: 114676.     CrossRef
Rosehip Extract-Functionalized Magnesium Hydroxide Nanoparticles and Its Effect on Osteoblastic and Osteoclastic Cells
Laura Costa Pinho, Thais Francini Garbieri, Liliana Grenho, Marta M. Alves, Pedro Sousa Gomes, Carlos Ferreira Santos, Maria Helena Fernandes, Catarina Santos, Bruno Colaço
Materials.2021; 14(15): 4172.     CrossRef
A unique epithelioid vascular neoplasm of bone characterized by EWSR1/FUS‐NFATC1/2 fusions
Nooshin K. Dashti, Brendan C. Dickson, Lei Zhang, Ziyu Xie, Gunnlaugur Pétur Nielsen, Cristina R. Antonescu
Genes, Chromosomes and Cancer.2021; 60(11): 762.     CrossRef
Bioactivity and Antibacterial Behaviors of Nanostructured Lithium-Doped Hydroxyapatite for Bone Scaffold Application
Pardis Keikhosravani, Hossein Maleki-Ghaleh, Amir Kahaie Khosrowshahi, Mahdi Bodaghi, Ziba Dargahi, Majid Kavanlouei, Pooriya Khademi-Azandehi, Ali Fallah, Younes Beygi-Khosrowshahi, M. Hossein Siadati
International Journal of Molecular Sciences.2021; 22(17): 9214.     CrossRef
Non-polar lipid from greenshell mussel (Perna canaliculus) inhibits osteoclast differentiation
Parkpoom Siriarchavatana, Marlena C. Kruger, Matthew R. Miller, Hong Tian, Frances M. Wolber
Bone Reports.2021; 15: 101132.     CrossRef
Psoraleae Semen Ethanol Extract Inhibits RANKL-Induced Osteoclast Differentiation and Osteoclast Specific Genes Expression
Gwang-hyun Ryu, Eom Ji Kim, Minsun Kim, Jae-Hyun Kim, Yujin Lee, Dae-hwan Jin, Youngjoo Sohn, Hyuk-Sang Jung
Korean Journal of Acupuncture.2021; 38(3): 140.     CrossRef
Effects of Bisphenol A and Its Alternatives, Bisphenol F and Tetramethyl Bisphenol F on Osteoclast Differentiation
Hye-Min Kim, Seon-Min Lee, Jungil Choi, Nak-Kyun Soung, Jeong-Doo Heo
Molecules.2021; 26(20): 6100.     CrossRef
IRF2 enhances RANKL-induced osteoclast differentiation via regulating NF-κB/NFATc1 signaling
Inyoung Kim, Jung Ha Kim, Kabsun Kim, Semun Seong, Keun-Bae Lee, Nacksung Kim
BMB Reports.2021; 54(9): 482.     CrossRef
GAP-43 ameliorates Podocyte injury by decreasing nuclear NFATc1 expression
Zhiwen Lian, Guibao Ke, Hong Zhang, Caoshuai Dou, Xueqin Chen, Bohou Li, Fengxia Zhang, Shichun Wen, Qiong Wu, Yubin Xia, Nan Jiang, Zhuo Li, Sijia Li, Xingchen Zhao, Jianchao Ma, Ting Lin, Feng Wen, Lixia Xu, Zhilian Li, Huabang Liang, Wei Dong, Yuanhan
Biochemistry and Biophysics Reports.2021; 28: 101145.     CrossRef
Toxic Effects of Indoxyl Sulfate on Osteoclastogenesis and Osteoblastogenesis
Jia-Fwu Shyu, Wen-Chih Liu, Cai-Mei Zheng, Te-Chao Fang, Yi-Chou Hou, Chiz-Tzung Chang, Ting-Ying Liao, Yin-Cheng Chen, Kuo-Cheng Lu
International Journal of Molecular Sciences.2021; 22(20): 11265.     CrossRef
Skeletal Deficits in Male and Female down Syndrome Model Mice Arise Independent of Normalized Dyrk1a Expression in Osteoblasts
Jared R. Thomas, Kourtney Sloan, Kelsey Cave, Joseph M. Wallace, Randall J. Roper
Genes.2021; 12(11): 1729.     CrossRef
Synergistic Effect of Biphasic Calcium Phosphate and Platelet-Rich Fibrin Attenuate Markers for Inflammation and Osteoclast Differentiation by Suppressing NF-κB/MAPK Signaling Pathway in Chronic Periodontitis
Anil Kumar, Jaideep Mahendra, Little Mahendra, Hesham H. Abdulkarim, Mohammed Sayed, Maryam H. Mugri, Zeeshan Heera Ahmad, Ashok Kumar Bhati, Hadeel Hussain Faqehi, Waleed Omar Algregri, Saranya Varadarajan, Thodur Madapusi Balaji, Hosam Ali Baeshen, Shan
Molecules.2021; 26(21): 6578.     CrossRef
Conversion of Osteoclasts into Bone-Protective, Tumor-Suppressing Cells
Ke-Xin Li, Xun Sun, Bai-Yan Li, Hiroki Yokota
Cancers.2021; 13(22): 5593.     CrossRef
Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity
Jun-ming Huang, Chen-zhong Wang, Shun-yi Lu, Zhe Wang, Zuo-qin Yan
Drug Design, Development and Therapy.2021; Volume 15: 4811.     CrossRef
Green-Synthesized Magnesium Hydroxide Nanoparticles Induced Osteoblastic Differentiation in Bone Co-Cultured Cells
Laura Costa Pinho, Marta M. Alves, Bruno Colaço, Maria Helena Fernandes, Catarina Santos
Pharmaceuticals.2021; 14(12): 1281.     CrossRef
The Neuropeptide VIP Limits Human Osteoclastogenesis: Clinical Associations with Bone Metabolism Markers in Patients with Early Arthritis
David Castro-Vazquez, Amalia Lamana, Paula Arribas-Castaño, Irene Gutiérrez-Cañas, Raúl Villanueva-Romero, Selene Pérez-García, Carmen Martínez, Yasmina Juarranz, Sara Fernández de Córdoba, Isidoro González-Álvaro, Rosa P. Gomariz, Mar Carrión
Biomedicines.2021; 9(12): 1880.     CrossRef
Age-related accumulation of advanced oxidation protein products promotes osteoclastogenesis through disruption of redox homeostasis
Jingshen Zhuang, Xuebing Chen, Guixing Cai, Dizheng Wu, Chen Tu, Siyuan Zhu, Yusheng Huang, Ping Xu, Zhaoming Zhong
Cell Death & Disease.2021;[Epub]     CrossRef
Propionibacterium freudenreichii Inhibits RANKL-Induced Osteoclast Differentiation and Ameliorates Rheumatoid Arthritis in Collagen-Induced Arthritis Mice
Jiah Yeom, Dong Joon Yim, Seongho Ma, Young-Hee Lim
Microorganisms.2021; 10(1): 48.     CrossRef
Bone Erosion in Inflammatory Arthritis is Attenuated by Trichinella spiralis Through Inhibiting M1 Monocyte/Macrophage Polarization
Yuli Cheng, Yan Yu, Qinghui Zhuang, Lei Wang, Bin Zhan, Yiqu Liu, Jingjing Huang, Junfeng Hao, Xinping Zhu
SSRN Electronic Journal .2021;[Epub]     CrossRef
Epigenetic and transcriptional regulation of osteoclast differentiation
Daisuke Kurotaki, Haruka Yoshida, Tomohiko Tamura
Bone.2020; 138: 115471.     CrossRef
Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy‐induced bone loss
Jia Wang, Hanfeng Guan, Hui Liu, Zuowei Lei, Honglei Kang, Qian Guo, Yimin Dong, Huiyong Liu, Yunlong Sun, Zhong Fang, Feng Li
Journal of Cellular and Molecular Medicine.2020; 24(3): 2294.     CrossRef
Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor
Wen-Chih Liu, Jia-Fwu Shyu, Paik Seong Lim, Te-Chao Fang, Chien-Lin Lu, Cai-Mei Zheng, Yi-Chou Hou, Chia-Chao Wu, Yuh-Feng Lin, Kuo-Cheng Lu
International Journal of Molecular Sciences.2020; 21(10): 3486.     CrossRef
3-Hydroxyolean-12-en-27-oic Acids Inhibit RANKL-Induced Osteoclastogenesis in Vitro and Inflammation-Induced Bone Loss in Vivo
Wonyoung Seo, Suhyun Lee, Phuong Thao Tran, Thi Quynh-Mai Ngo, Okwha Kim, Thanh Huong Le, Nguyen Hai Dang, Cheol Hwangbo, Byung Sun Min, Jeong-Hyung Lee
International Journal of Molecular Sciences.2020; 21(15): 5240.     CrossRef
Ethyl Acetate Fraction of Aqueous Extract of Lentinula edodes Inhibits Osteoclastogenesis by Suppressing NFATc1 Expression
Hyerim Lee, Kyubin Lee, Sheunghun Lee, Jisu Lee, Won Tae Jeong, Heung Bin Lim, Tae Kyung Hyun, Sun-Ju Yi, Kyunghwan Kim
International Journal of Molecular Sciences.2020; 21(4): 1347.     CrossRef
Epigenetic and transcriptional regulation of osteoclastogenesis in the pathogenesis of skeletal diseases: A systematic review
Siddhartha Sharma, Aditi Mahajan, Anupam Mittal, Riddhi Gohil, Sunny Sachdeva, Shahnawaz Khan, Mandeep Dhillon
Bone.2020; 138: 115507.     CrossRef
Anemonin Attenuates RANKL-Induced Osteoclastogenesis and Ameliorates LPS-Induced Inflammatory Bone Loss in Mice via Modulation of NFATc1
Huanhuan Hou, Qisheng Peng, Shaoming Wang, Yuxin Zhang, Jinjin Cao, Yuming Deng, Yingjian Wang, Wan-chun Sun, Hong-bing Wang
Frontiers in Pharmacology.2020;[Epub]     CrossRef
Modified Quinoxaline‐Fused Oleanolic Acid Derivatives as Inhibitors of Osteoclastogenesis and Potential Agent in Anti‐Osteoporosis
Yu‐Chao Zhang, Qi Shen, Ming‐Wu Zhu, Jie Wang, Yun Du, Jing Wu, Jian‐Xin Li
ChemistrySelect.2020; 5(4): 1526.     CrossRef
A Synthetic Peptide, CK2.3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway
John Nguyen, Semaj Kelly, Ryan Wood, Brian Heubel, Anja Nohe
Journal of Developmental Biology.2020; 8(3): 12.     CrossRef
A Sub-Clone of RAW264.7-Cells Form Osteoclast-Like Cells Capable of Bone Resorption Faster than Parental RAW264.7 through Increased De Novo Expression and Nuclear Translocation of NFATc1
Laia Mira-Pascual, Anh N. Tran, Göran Andersson, Tuomas Näreoja, Pernilla Lång
International Journal of Molecular Sciences.2020; 21(2): 538.     CrossRef
The extract of Trachelospermum jasminoides (Lindl.) Lem. vines inhibits osteoclast differentiation through the NF-κB, MAPK and AKT signaling pathways
Tao Jiang, Wei Yan, Bo Kong, Changgui Wu, Kai Yang, Tianqi Wang, Xueming Yan, Lei Guo, Ping Huang, Min Jiang, Xiaobing Xi, Xing Xu
Biomedicine & Pharmacotherapy.2020; 129: 110341.     CrossRef
Flufenamic acid inhibits osteoclast formation and bone resorption and act against estrogen-dependent bone loss in mice
Shutao Zhang, Shicheng Huo, Hui Li, Haozheng Tang, Bin'en Nie, Xinhua Qu, Bing Yue
International Immunopharmacology.2020; 78: 106014.     CrossRef
Hederagenin protects mice against ovariectomy-induced bone loss by inhibiting RANKL-induced osteoclastogenesis and bone resorption
Kun Tian, Yuangang Su, Jiaxin Ding, Dairong Wang, Yunfei Zhan, Yicheng Li, Jiamin Liang, Xixi Lin, Fangming Song, Ziyi Wang, Jiake Xu, Qian Liu, Jinmin Zhao
Life Sciences.2020; 244: 117336.     CrossRef
Inhibition of osteoclasts differentiation by CDC2-induced NFATc1 phosphorylation
Hye-min Kim, Long He, Sangku Lee, Chanmi Park, Dong Hyun Kim, Ho-Jin Han, Junyeol Han, Joonsung Hwang, Hyunjoo Cha-Molstad, Kyung Ho Lee, Sung-Kyun Ko, Jae-Hyuk Jang, In-Ja Ryoo, John Blenis, Hee Gu Lee, Jong Seog Ahn, Yong Tae Kwon, Nak-Kyun Soung, Bo Ye
Bone.2020; 131: 115153.     CrossRef
p53 positively regulates osteoprotegerin-mediated inhibition of osteoclastogenesis by downregulating TSC2-induced autophagy in vitro
Xishuai Tong, Jianhong Gu, Miaomiao Chen, Tao Wang, Hui Zou, Ruilong Song, Hongyan Zhao, Jianchun Bian, Zongping Liu
Differentiation.2020; 114: 58.     CrossRef
Inhibitory effect of Chaenomelis Fructus ethanol extract on receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenesis
Geun Ha Park, Dong Ryun Gu, Seoung Hoon Lee
International Journal of Oral Biology.2020; 45(1): 15.     CrossRef
Density and function of actin-microdomains in healthy and NF1 deficient osteoclasts revealed by the combined use of atomic force and stimulated emission depletion microscopy
Takahiro Deguchi, Elnaz Fazeli, Sami Koho, Paula Pennanen, Maria Alanne, Mayank Modi, John E Eriksson, Kari V Vienola, Pekka E Hänninen, Juha Peltonen, Tuomas Näreoja
Journal of Physics D: Applied Physics.2020; 53(1): 014003.     CrossRef
Lactobacillus plantarum GKM3 and Lactobacillus paracasei GKS6 Supplementation Ameliorates Bone Loss in Ovariectomized Mice by Promoting Osteoblast Differentiation and Inhibiting Osteoclast Formation
Li-Chan Yang, Shih-Wei Lin, I-Chen Li, Yen-Po Chen, Shih-Yang Tzu, Wei Chou, Chin-Chu Chen, Wen-Chuan Lin, Yen-Lien Chen, Wen-Hsin Lin
Nutrients.2020; 12(7): 1914.     CrossRef
Ferryl Hemoglobin Inhibits Osteoclastic Differentiation of Macrophages in Hemorrhaged Atherosclerotic Plaques
Erzsébet Zavaczki, Tamás Gáll, Abolfazl Zarjou, Zoltán Hendrik, László Potor, Csaba Zsigmond Tóth, Gábor Méhes, Ágnes Gyetvai, Anupam Agarwal, György Balla, József Balla
Oxidative Medicine and Cellular Longevity.2020; 2020: 1.     CrossRef
Current perspectives of osteoclastogenesis through estrogen modulated immune cell cytokines
Isadora Akemi Uehara, Luiz Ricardo Soldi, Marcelo José Barbosa Silva
Life Sciences.2020; 256: 117921.     CrossRef
Multi-omics Data Integration for Identifying Osteoporosis Biomarkers and Their Biological Interaction and Causal Mechanisms
Chuan Qiu, Fangtang Yu, Kuanjui Su, Qi Zhao, Lan Zhang, Chao Xu, Wenxing Hu, Zun Wang, Lanjuan Zhao, Qing Tian, Yuping Wang, Hongwen Deng, Hui Shen
iScience.2020; 23(2): 100847.     CrossRef
Macrolactin A protects against LPS-induced bone loss by regulation of bone remodeling
Mahesh Sapkota, Ming Gao, Liang Li, Ming Yang, Saroj Kumar Shrestha, Hyukjae Choi, Yunjo Soh
European Journal of Pharmacology.2020; 883: 173305.     CrossRef
Arctiin abrogates osteoclastogenesis and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation
Delong Chen, Zhen Ye, Chao Wang, Qingqing Wang, Haibin Wang, Vincent Kuek, Ziyi Wang, Heng Qiu, Jinbo Yuan, Jacob Kenny, Fan Yang, Jianbo He, Yun Liu, Gang Wang, Meng Zhang, Gangyu Zhang, Junjian Wang, Peng Chen, Jiake Xu
Pharmacological Research.2020; 159: 104944.     CrossRef
Osthole‐loaded N‐octyl‐O‐sulfonyl chitosan micelles (NSC‐OST) inhibits RANKL‐induced osteoclastogenesis and prevents ovariectomy‐induced bone loss in rats
Lining Wang, Suyang Zheng, Guicheng Huang, Jie Sun, Yalan Pan, Yuhao Si, Pengcheng Tu, Guihua Xu, Yong Ma, Yang Guo
Journal of Cellular and Molecular Medicine.2020; 24(7): 4105.     CrossRef
A Novel Sandwich ELISA for Tartrate-Resistant Acid Phosphatase 5a and 5b Protein Reveals that Both Isoforms are Secreted by Differentiating Osteoclasts and Correlate to the Type I Collagen Degradation Marker CTX-I In Vivo and In Vitro
Laia Mira-Pascual, Christina Patlaka, Suchita Desai, Staffan Paulie, Tuomas Näreoja, Pernilla Lång, Göran Andersson
Calcified Tissue International.2020; 106(2): 194.     CrossRef
Inhibitory Effect of Rosae Multiflorae Fructus Extracts on the Receptor Activator of NF-κB Ligand-Induced Osteoclastogenesis through Modulation of P38- and Ca2+-Mediated Nuclear Factor of Activated T-Cells Cytoplasmic 1 Expression
Keun Ha Park, Dong Ryun Gu, Min Seuk Kim, Seoung Hoon Lee
Journal of Bone Metabolism.2020; 27(1): 53.     CrossRef
Poncirin Inhibits Osteoclast Differentiation and Bone Loss through Down-Regulation of NFATc1In VitroandIn Vivo
Kwang-Hoon Chun, Hyun Chul Jin, Ki Sung Kang, Tong-Shin Chang, Gwi Seo Hwang
Biomolecules & Therapeutics.2020; 28(4): 337.     CrossRef
Inhibition of MEK/ERK upregulates GSH production and increases RANKL-induced osteoclast differentiation in RAW 264.7 cells
Taiwo Samuel Agidigbi, In Soon Kang, Chaekyun Kim
Free Radical Research.2020; 54(11-12): 894.     CrossRef
Felodipine blocks osteoclast differentiation and ameliorates estrogen-dependent bone loss in mice by modulating p38 signaling pathway
Shutao Zhang, Hui Li, Haozheng Tang, Shicheng Huo, Bin'en Nie, Xinhua Qu, Bing Yue
Experimental Cell Research.2020; 387(2): 111800.     CrossRef
Multiple Myeloma-Derived Extracellular Vesicles Induce Osteoclastogenesis through the Activation of the XBP1/IRE1α Axis
Lavinia Raimondi, Angela De Luca, Simona Fontana, Nicola Amodio, Viviana Costa, Valeria Carina, Daniele Bellavia, Stefania Raimondo, Sergio Siragusa, Francesca Monteleone, Riccardo Alessandro, Milena Fini, Gianluca Giavaresi
Cancers.2020; 12(8): 2167.     CrossRef
Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages
Alicia Bellomo, Isabelle Mondor, Lionel Spinelli, Marine Lagueyrie, Benjamin J. Stewart, Nicolas Brouilly, Bernard Malissen, Menna R. Clatworthy, Marc Bajénoff
Immunity.2020; 53(1): 127.     CrossRef
Transcriptional Regulation of Osteoclastogenesis: The Emerging Role of KLF2
Daniela Rolph, Hiranmoy Das
Frontiers in Immunology.2020;[Epub]     CrossRef
Polysaccharides isolated from lotus leaves (LLEP) exert anti-osteoporotic effects by inhibiting osteoclastogenesis
Youn-Hwan Hwang, Seon-A Jang, Ami Lee, Chang-Won Cho, Young-Ran Song, Hee-Do Hong, Hyunil Ha, Taesoo Kim
International Journal of Biological Macromolecules.2020; 161: 449.     CrossRef
Egg-Derived Tripeptide IRW Attenuates LPS-Induced Osteoclastogenesis in RAW 264.7 Macrophages via Inhibition of Inflammatory Responses and NF-κB/MAPK Activation
Nan Shang, Jianping Wu
Journal of Agricultural and Food Chemistry.2020; 68(22): 6132.     CrossRef
Effect of echinalkamide identified from Echinacea purpurea (L.) Moench on the inhibition of osteoclastogenesis and bone resorption
Bo Yoon Chang, Seul Ki Lee, Da Eun Kim, Jin Hye Bae, Thanh Tam Ho, So-Young Park, Mi Kyeong Lee, Sung Yeon Kim
Scientific Reports.2020;[Epub]     CrossRef
Accelerated osteoblastic differentiation in patient-derived dental pulp stem cells carrying a gain-of-function mutation of TRPV4 associated with metatropic dysplasia
Xu Han, Hiroki Kato, Hiroshi Sato, Yuta Hirofuji, Satoshi Fukumoto, Keiji Masuda
Biochemical and Biophysical Research Communications.2020; 523(4): 841.     CrossRef
Transcriptome Analysis Reveals That Abeliophyllum distichum Nakai Extract Inhibits RANKL-Mediated Osteoclastogenensis Mainly through Suppressing Nfatc1 Expression
Kyubin Lee, You-Jee Jang, Hyerim Lee, Eunbin Kim, Yeojin Kim, Tong-Kewn Yoo, Tae Kyung Hyun, Jae-Il Park, Sun-Ju Yi, Kyunghwan Kim
Biology.2020; 9(8): 212.     CrossRef

Sarsasapogenin Suppresses RANKL-Induced Osteoclastogenesis in vitro and Prevents Lipopolysaccharide-Induced Bone Loss in vivo

Jiaxuan Peng, Kangxian Zhao, Jiling Zhu, Yanben Wang, Peng Sun, Qichang Yang, Tan Zhang, Weiqi Han, Wenjun Hu, Wanlei Yang, Jianwei Ruan, Yu Qian
Drug Design, Development and Therapy.2020; Volume 14: 3435.     CrossRef
Uncaria tomentosa reduces osteoclastic bone loss in vivo
Vilma Lima, Iracema Matos Melo, Thaise Mayumi Taira, Liseth Yamile Wilches Buitrago, Cristiane Sá Roriz Fonteles, Luzia Kalyne Almeida Moreira Leal, Ana Sheila de Queiroz Souza, Talysson Silva Almeida, Raimundo Nogueira da Costa Filho, Manoel Odorico Mora
Phytomedicine.2020; 79: 153327.     CrossRef
Impact of iron overload on bone remodeling in thalassemia
Pokpong Piriyakhuntorn, Adisak Tantiworawit, Mattabhorn Phimphilai, Krekwit Shinlapawittayatorn, Siriporn C. Chattipakorn, Nipon Chattipakorn
Archives of Osteoporosis.2020;[Epub]     CrossRef
Osteoclasts and Microgravity
John Kelly Smith
Life.2020; 10(9): 207.     CrossRef
Maackiain dampens osteoclastogenesis via attenuating RANKL‐stimulated NF‐κB signalling pathway and NFATc1 activity
Yuhao Liu, Weizai Zeng, Chao Ma, Ziyi Wang, Chao Wang, Shaobin Li, Wei He, Qingwen Zhang, Jiake Xu, Chi Zhou
Journal of Cellular and Molecular Medicine.2020; 24(21): 12308.     CrossRef
N-[2-(4-Acetyl-1-Piperazinyl)Phenyl]-2-(3-Methylphenoxy)Acetamide (NAPMA) Inhibits Osteoclast Differentiation and Protects against Ovariectomy-Induced Osteoporosis
Jinkyung Lee, Sun-Hee Ahn, Zhihao Chen, Sohi Kang, Dong Kyu Choi, Changjong Moon, Sang Hyun Min, Byung-Ju Park, Tae-Hoon Lee
Molecules.2020; 25(20): 4855.     CrossRef
Scl-Ab reverts pro-osteoclastogenic signalling and resorption in estrogen deficient osteocytes
H. Allison, G. Holdsworth, L. M. McNamara
BMC Molecular and Cell Biology.2020;[Epub]     CrossRef
Effects of Erythropoietin in White Adipose Tissue and Bone Microenvironment
Sukanya Suresh, Jeeyoung Lee, Constance Tom Noguchi
Frontiers in Cell and Developmental Biology.2020;[Epub]     CrossRef
Tetrandrine Inhibits Titanium Particle-Induced Inflammatory Osteolysis through the Nuclear Factor-κB Pathway
Zige Liu, Yan Li, Fengying Guo, Chen Zhang, Guorui Song, Jiahao Yang, Desheng Chen, Marietta Herrmann
Mediators of Inflammation.2020; 2020: 1.     CrossRef
Vitamin K and Osteoporosis
Maria Fusaro, Giuseppe Cianciolo, Maria Luisa Brandi, Serge Ferrari, Thomas L. Nickolas, Giovanni Tripepi, Mario Plebani, Martina Zaninotto, Giorgio Iervasi, Gaetano La Manna, Maurizio Gallieni, Roberto Vettor, Andrea Aghi, Lorenzo Gasperoni, Sandro Giann
Nutrients.2020; 12(12): 3625.     CrossRef
The Role of Toll-Like Receptors in Osteoclastogenesis
Mijung Yim
Journal of Bone Metabolism.2020; 27(4): 227.     CrossRef
Molecular Signaling Pathways and Essential Metabolic Elements in Bone Remodeling: An Implication of Therapeutic Targets for Bone Diseases
Aditi Sharma, Lalit Sharma, Rohit Goyal
Current Drug Targets.2020; 22(1): 77.     CrossRef
MicroRNAs: Key Regulators to Understand Osteoclast Differentiation?
Claire Lozano, Isabelle Duroux-Richard, Hüseyin Firat, Eric Schordan, Florence Apparailly
Frontiers in Immunology.2019;[Epub]     CrossRef
A catalog of single nucleotide changes distinguishing modern humans from archaic hominins
Martin Kuhlwilm, Cedric Boeckx
Scientific Reports.2019;[Epub]     CrossRef
PSTP-3,5-Me Inhibits Osteoclast Differentiation and Bone Resorption
Eunjin Cho, Zhihao Chen, Jinkyung Lee, Sunwoo Lee, Tae-Hoon Lee
Molecules.2019; 24(18): 3346.     CrossRef
Ankle loading ameliorates bone loss from breast cancer–associated bone metastasis
Shuang Yang, Hong Liu, Lei Zhu, Xinle Li, Daquan Liu, Xiaomeng Song, Hiroki Yokota, Ping Zhang
The FASEB Journal.2019; 33(10): 10742.     CrossRef
Bone Remodeling: Histone Modifications as Fate Determinants of Bone Cell Differentiation
Sun-Ju Yi, Hyerim Lee, Jisu Lee, Kyubin Lee, Junil Kim, Yeojin Kim, Jae-Il Park, Kyunghwan Kim
International Journal of Molecular Sciences.2019; 20(13): 3147.     CrossRef
The use of apocynin inhibits osteoclastogenesis
Mariana Pena Ribeiro Soares, Danielle Pereira Silva, Isadora Akemi Uehara, Erivan Schnaider Ramos, Paulo Vinicius Gil Alabarse, Sandra Yasuyo Fukada, Felipe Cordero da Luz, Leda Quercia Vieira, Ana Paula Lima Oliveira, Marcelo José Barbosa Silva
Cell Biology International.2019; 43(5): 466.     CrossRef
Fructose 1,6-bisphosphate inhibits osteoclastogenesis by attenuating RANKL-induced NF-κB/NFATc-1
L. Wilches-Buitrago, P. R. Viacava, F. Q. Cunha, J. C. Alves-Filho, S. Y. Fukada
Inflammation Research.2019; 68(5): 415.     CrossRef
Anacardic acid inhibits RANKL‐induced osteoclastogenesis in vitro and prevents ovariectomy‐induced bone loss in vivo
Kangxian Zhao, Yewei Jia, Jiaxuan Peng, Cong Pang, Tan Zhang, Weiqi Han, Jiawei Jiang, Xuanyuan Lu, Jiling Zhu, Yu Qian
The FASEB Journal.2019; 33(8): 9100.     CrossRef
Cepharanthine suppresses osteoclast formation by modulating the nuclear factor‐κB and nuclear factor of activated T‐cell signaling pathways
Xixi Lin, Fangming Song, Lin Zhou, Ziyi Wang, Chengming Wei, Jiake Xu, Jinmin Zhao, Qian Liu
Journal of Cellular Biochemistry.2019; 120(2): 1990.     CrossRef
Role of APD-Ribosylation in Bone Health and Disease
Wang, Mbalaviele
Cells.2019; 8(10): 1201.     CrossRef
Development of PEI-RANK siRNA Complex Loaded PLGA Nanocapsules for the Treatment of Osteoporosis
Deniz Sezlev Bilecen, Hasan Uludag, Vasif Hasirci
Tissue Engineering Part A.2019; 25(1-2): 34.     CrossRef
Madecassoside inhibits estrogen deficiency‐induced osteoporosis by suppressing RANKL‐induced osteoclastogenesis
Qingqing Wang, Lingya Yao, Ke Xu, Haiming Jin, Kai Chen, Ziyi Wang, Qian Liu, Zhen Cao, Jacob kenny, Yuhao Liu, Jennifer Tickner, Huazi Xu, Jiake Xu
Journal of Cellular and Molecular Medicine.2019; 23(1): 380.     CrossRef
Inhibition of osteoclastogenesis by mechanically stimulated osteoblasts is attenuated during estrogen deficiency
H. Allison, L. M. McNamara
American Journal of Physiology-Cell Physiology.2019; 317(5): C969.     CrossRef
Update on the role of Sirtuin 3 in cell differentiation: A major metabolic target that can be pharmacologically controlled
Julie Storder, Patricia Renard, Thierry Arnould
Biochemical Pharmacology.2019; 169: 113621.     CrossRef
Beneficial Effects of Total Phenylethanoid Glycoside Fraction Isolated from Cistanche deserticola on Bone Microstructure in Ovariectomized Rats
Lingling Yang, Shuqin Ding, Bo Zhang, Jingjing Liu, Yanhong Dong, Qiwen Tang, Pingping Yang, Xueqin Ma
Oxidative Medicine and Cellular Longevity.2019; 2019: 1.     CrossRef
Mannan-Binding Lectin Attenuates Inflammatory Arthritis Through the Suppression of Osteoclastogenesis
Lijun Dong, Jun Wu, Kai Chen, Jingwen Xie, Youyi Wang, Dantong Li, Yunzhi Liu, Aiping Yin, Yue Zhao, Yunpeng Han, Jia Zhou, Liyun Zhang, Zhengliang Chen, Daming Zuo
Frontiers in Immunology.2019;[Epub]     CrossRef
Stimuli and Relevant Signaling Cascades for NFATc1 in Bone Cell Homeostasis: Friend or Foe?
Zhen Zhang, Hao Wen, Xiaobin Yang, Ke Zhang, Baorong He, Xinliang Zhang, Lingbo Kong
Current Stem Cell Research & Therapy.2019; 14(3): 239.     CrossRef
AP‐1 and Mitf interact with NFATc1 to stimulate cathepsin K promoter activity in osteoclast precursors
Manhui Pang, Maria Rodríguez‐Gonzalez, Mireya Hernandez, Claudia Carolina Recinos, Kenneth Ladd Seldeen, Bruce Robert Troen
Journal of Cellular Biochemistry.2019; 120(8): 12382.     CrossRef
A Novel Small Molecule Which Increases Osteoprotegerin Expression and Protects Against Ovariectomy-Related Bone Loss in Rats
Xiaowan Han, Shiqiang Gong, Ni Li, Xiao Wang, Peng Liu, Yanni Xu, Xiaobo He, Wei Jiang, Shuyi Si
Frontiers in Pharmacology.2019;[Epub]     CrossRef
Haptoglobin Acts as a TLR4 Ligand to Suppress Osteoclastogenesis via the TLR4–IFN-β Axis
Jun-Oh Kwon, Won Jong Jin, Bongjun Kim, Hyunil Ha, Hong-Hee Kim, Zang Hee Lee
The Journal of Immunology.2019; 202(12): 3359.     CrossRef
Leonurus�sibiricus L. ethanol extract promotes osteoblast differentiation and inhibits osteoclast formation
Jae‑Hyun Kim, Minsun Kim, Hyuk‑Sang Jung, Youngjoo Sohn
International Journal of Molecular Medicine.2019;[Epub]     CrossRef
Epigenetic regulation of NfatC1 transcription and osteoclastogenesis by nicotinamide phosphoribosyl transferase in the pathogenesis of arthritis
Xuanan Li, Shamima Islam, Min Xiong, Ndona N. Nsumu, Mark W. Lee, Li Qin Zhang, Yasuyoshi Ueki, Daniel P. Heruth, Guanghua Lei, Shui Qing Ye
Cell Death Discovery.2019;[Epub]     CrossRef
Scutellarein inhibits RANKL‐induced osteoclast formation in vitro and prevents LPS‐induced bone loss in vivo
Fangsheng Fu, Siyuan Shao, Ziyi Wang, Fangming Song, Xixi Lin, Jiaxin Ding, Chen Li, Zuoxing Wu, Kai Li, Yu Xiao, Yiji Su, Jinmin Zhao, Qian Liu, Jiake Xu
Journal of Cellular Physiology.2019; 234(7): 11951.     CrossRef
Hexane Fraction of Turbo brunneus Inhibits Intermediates of RANK-RANKL Signaling Pathway and Prevent Ovariectomy Induced Bone Loss
Sachin Chaugule, Shalini Kashipathi Sureshbabu, Suresh Dakave, C. Murali Krishna, Pradip Chaudhari, Madhavi Indap, Shubhada Chiplunkar
Frontiers in Endocrinology.2019;[Epub]     CrossRef
Identification of anti-osteoclastogenic compounds from Cleistocalyx operculatus flower buds and their effects on RANKL-induced osteoclastogenesis
Phuong Thao Tran, Thi Quynh-Mai Ngo, Suhyun Lee, Okwha Kim, Huynh Nguyen Khanh Tran, Cheol Hwangbo, Byung Sun Min, Jeong-Hyung Lee
Journal of Functional Foods.2019; 60: 103388.     CrossRef
LYN, a key mediator in estrogen-dependent suppression of osteoclast differentiation, survival, and function
Shubhangi Gavali, Manoj Kumar Gupta, Bhavna Daswani, Mohan R. Wani, Ravi Sirdeshmukh, M. Ikram Khatkhatay
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2019; 1865(3): 547.     CrossRef
Lycopus lucidus Turcz Inhibits the Osteoclastogenesis in RAW 264.7 Cells and Bone Loss in Ovariectomized Rat Model
Da-Won Jeong, Eun-Young Kim, Jae-Hyun Kim, Bina Lee, SooYeon Hong, Jae Ho Park, Hyuk-Sang Jung, Youngjoo Sohn
Evidence-Based Complementary and Alternative Medicine.2019; 2019: 1.     CrossRef
Role of anoctamin 5, a gene associated with gnathodiaphyseal dysplasia, in osteoblast and osteoclast differentiation
Jung Ha Kim, Kabsun Kim, Inyoung Kim, Semun Seong, Sang Wan Kim, Nacksung Kim
Bone.2019; 120: 432.     CrossRef
Protective effects of a polysaccharide BLE0 isolated from barley leaf on bone loss in ovariectomized mice
Youn-Hwan Hwang, Hyunil Ha, Rajeong Kim, Chang-Won Cho, Young-Ran Song, Hee-Do Hong, Taesoo Kim
International Journal of Biological Macromolecules.2019; 123: 314.     CrossRef
Modulating calcium‐mediated NFATc1 and mitogen‐activated protein kinase deactivation underlies the inhibitory effects of kavain on osteoclastogenesis and bone resorption
Qiang Guo, Zhen Cao, Bo Wu, Fangxiao Chen, Jennifer Tickner, Ziyi Wang, Heng Qiu, Chao Wang, Kai Chen, Renxiang Tan, Qile Gao, Jiake Xu
Journal of Cellular Physiology.2019; 234(1): 789.     CrossRef
Cyclolinopeptide F, a cyclic peptide from flaxseed inhibited RANKL-induced osteoclastogenesis via downergulation of RANK expression
Toshio Kaneda, Yuki Nakajima, Sae Koshikawa, Alfarius Eko Nugroho, Hiroshi Morita
Journal of Natural Medicines.2019; 73(3): 504.     CrossRef
Long noncoding RNAs: a missing link in osteoporosis
Andreia Machado Silva, Sara Reis Moura, José Henrique Teixeira, Mário Adolfo Barbosa, Susana Gomes Santos, Maria Inês Almeida
Bone Research.2019;[Epub]     CrossRef
Ameloblastin attenuates RANKL‐mediated osteoclastogenesis by suppressing activation of nuclear factor of activated T‐cell cytoplasmic 1 (NFATc1)
Wichida Chaweewannakorn, Wataru Ariyoshi, Toshinori Okinaga, Yuko Fujita, Kenshi Maki, Tatsuji Nishihara
Journal of Cellular Physiology.2019; 234(2): 1745.     CrossRef
KBTBD11, a novel BTB-Kelch protein, is a negative regulator of osteoclastogenesis through controlling Cullin3-mediated ubiquitination of NFATc1
Shun Narahara, Eiko Sakai, Tomoko Kadowaki, Yu Yamaguchi, Haruna Narahara, Kuniaki Okamoto, Izumi Asahina, Takayuki Tsukuba
Scientific Reports.2019;[Epub]     CrossRef
LncRNA‐Jak3:Jak3 coexpressed pattern regulates monosodium urate crystal‐induced osteoclast differentiation through Nfatc1/Ctsk expression
Chi‐Pin Lee, Yu‐Nan Huang, Srinivasan Nithiyanantham, Chung‐Ming Huang, Ying‐Chin Ko
Environmental Toxicology.2019; 34(2): 179.     CrossRef
Effects of hydroxyapatite surface nano/micro-structure on osteoclast formation and activity
Fuying Chen, Menglu Wang, Jing Wang, Xuening Chen, Xiangfeng Li, Yumei Xiao, Xingdong Zhang
Journal of Materials Chemistry B.2019; 7(47): 7574.     CrossRef
NHA2 promotes cyst development in an in vitro model of polycystic kidney disease
Hari Prasad, Donna K. Dang, Kalyan C. Kondapalli, Niranjana Natarajan, Valeriu Cebotaru, Rajini Rao
The Journal of Physiology.2019; 597(2): 499.     CrossRef
Black Rice (Oryza sativaL.) Fermented withLactobacillus caseiAttenuates Osteoclastogenesis and Ovariectomy-Induced Osteoporosis
Young Min Lee, In Sook Kim, Beong Ou Lim
BioMed Research International.2019; 2019: 1.     CrossRef
Humanin suppresses receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation via AMP-activated protein kinase activation
Namju Kang, Ki Woo Kim, Dong Min Shin
The Korean Journal of Physiology & Pharmacology.2019; 23(5): 411.     CrossRef
A Mini-Review: The Therapeutic Potential of Bone Marrow Mesenchymal Stem Cells and Relevant Signaling Cascades
Wen Yang, Bo Ma
Current Stem Cell Research & Therapy.2019; 14(3): 214.     CrossRef
RANKL-induced osteoclastogenesis in bone marrow-derived macrophages is suppressed by cisapride
Kyung-Ran Park, Hyung-Mun Yun
Toxicology.2019; 422: 95.     CrossRef
Ethanol extract of Polyscias fruticosa leaves suppresses RANKL-mediated osteoclastogenesis in vitro and LPS-induced bone loss in vivo
Phuong Thao Tran, Nguyen Hai Dang, Okhwa Kim, Pham Van Cuong, Nguyen Tien Dat, Cheol Hwangbo, Chau Van Minh, Jeong-Hyung Lee
Phytomedicine.2019; 59: 152908.     CrossRef
Osteoclastic expression of higher-level regulators NFATc1 and BCL6 in medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis
Falk Wehrhan, Christian Gross, Kay Creutzburg, Kerstin Amann, Jutta Ries, Marco Kesting, Carol-Immanuel Geppert, Manuel Weber
Journal of Translational Medicine.2019;[Epub]     CrossRef
Effects of mineral trioxide aggregate and bioceramics on macrophage differentiation and polarization in vitro
Ming-Gene Tu, Kuo-Ting Sun, Tong-Hong Wang, Yun-Zhen He, Shih-Min Hsia, Bi-He Tsai, Yin-Hwa Shih, Tzong-Ming Shieh
Journal of the Formosan Medical Association.2019; 118(10): 1458.     CrossRef
Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL‐induced osteoclastogenesis
Haiming Jin, Qingqing Wang, Kai Chen, Ke Xu, Hao Pan, Feifan Chu, Zhen Ye, Ziyi Wang, Jennifer Tickner, Heng Qiu, Chao Wang, Jacob Kenny, Huazi Xu, Te Wang, Jiake Xu
Journal of Cellular and Molecular Medicine.2019; 23(12): 8355.     CrossRef
Inhibitory Effects of N-[2-(4-acetyl-1-piperazinyl) phenyl]-2-(2-chlorophenoxy) acetamide on Osteoclast Differentiation In Vitro via the Downregulation of TRAF6
Zhihao Chen, Eunjin Cho, Jinkyung Lee, Sunwoo Lee, Tae-Hoon Lee
International Journal of Molecular Sciences.2019; 20(20): 5196.     CrossRef
Targeted sequencing of DCSTAMP in familial Paget's disease of bone
M.A. Sultana, N.J. Pavlos, Lynley Ward, J.P. Walsh, S.L. Rea
Bone Reports.2019; 10: 100198.     CrossRef
Forsythia suspensa Protects against Bone Loss in Ovariectomized Mice
Youn-Hwan Hwang, Seon-A Jang, Taesoo Kim, Hyunil Ha
Nutrients.2019; 11(8): 1831.     CrossRef
Fucoidan Prevents RANKL-Stimulated Osteoclastogenesis and LPS-Induced Inflammatory Bone Loss via Regulation of Akt/GSK3β/PTEN/NFATc1 Signaling Pathway and Calcineurin Activity
Sheng-Hua Lu, Yi-Jan Hsia, Kuang-Chung Shih, Tz-Chong Chou
Marine Drugs.2019; 17(6): 345.     CrossRef
Disulfiram suppressed ethanol promoted RANKL-induced osteoclastogenesis in vitro and ethanol-induced osteoporosis in vivo via ALDH1A1-NFATc1 axis
Yewei Jia, Jiawei Jiang, Kangxian Zhao, Tan Zhang, Peng Sun, Jiaxuan Peng, Qichang Yang, Yu Qian
Aging.2019; 11(19): 8103.     CrossRef
Evaluation of orthodontic tooth movement by 3D micro-computed tomography (µ-CT) following caffeine administration
H. Herniyati, Happy Harmono, Leliana Sandra Devi, Sri Hernawati
Dental Journal.2019; 52(1): 1.     CrossRef
Dehydrodiconiferyl Alcohol Inhibits Osteoclast Differentiation and Ovariectomy-Induced Bone Loss through Acting as an Estrogen Receptor Agonist
Wonwoo Lee, Kyeong Ryang Ko, Hyun-keun Kim, Doo Suk Lee, In-Jeong Nam, Seonung Lim, Sunyoung Kim
Journal of Natural Products.2018; 81(6): 1343.     CrossRef
Inhibitory activity of linarin on osteoclastogenesis through receptor activator of nuclear factor κB ligand-induced NF-κB pathway
Junsheng Wang, Bin Fu, Fuchun Lu, Xiaowu Hu, Jinshan Tang, Lixin Huang
Biochemical and Biophysical Research Communications.2018; 495(3): 2133.     CrossRef
Prevention and Treatment of Osteoporosis Using Chinese Medicinal Plants: Special Emphasis on Mechanisms of Immune Modulation
Hongyan Zhao, Ning Zhao, Peng Zheng, Xiaohong Xu, Meijie Liu, Dan Luo, Huihui Xu, Dahong Ju
Journal of Immunology Research.2018; 2018: 1.     CrossRef
Influence of Iron on Bone Homeostasis
Enikő Balogh, György Paragh, Viktória Jeney
Pharmaceuticals.2018; 11(4): 107.     CrossRef
Meta-Analysis of Genome-Wide Association Studies Identifies Novel Functional CpG-SNPs Associated with Bone Mineral Density at Lumbar Spine
Chuan Qiu, Hui Shen, Xiaoying Fu, Chao Xu, Hongwen Deng
International Journal of Genomics.2018; 2018: 1.     CrossRef
Common signalling pathways in macrophage and osteoclast multinucleation
Marie Pereira, Enrico Petretto, Siamon Gordon, J. H. Duncan Bassett, Graham R. Williams, Jacques Behmoaras
Journal of Cell Science.2018;[Epub]     CrossRef
Gα12 regulates osteoclastogenesis by modulating NFATc1 expression
Min‐Kyoung Song, Cheolkyu Park, Yong Deok Lee, Haemin Kim, Min Kyung Kim, Jun‐Oh Kwon, Ja Hyun Koo, Min Sung Joo, Sang Geon Kim, Hong‐Hee Kim
Journal of Cellular and Molecular Medicine.2018; 22(2): 849.     CrossRef
Periodontal materials and cell biology for guided tissue and bone regeneration
Mihai Andrei, Anca Dinischiotu, Andreea Cristiana Didilescu, Daniela Ionita, Ioana Demetrescu
Annals of Anatomy - Anatomischer Anzeiger.2018; 216: 164.     CrossRef
Inhibitory Effects of Standardized Boesenbergia pandurata Extract and Its Active Compound Panduratin A on Lipopolysaccharide-Induced Periodontal Inflammation and Alveolar Bone Loss in Rats
Haebom Kim, Changhee Kim, Kyo Eun Kook, Yanti, Seungmok Choi, Wonku Kang, Jae-Kwan Hwang
Journal of Medicinal Food.2018; 21(10): 961.     CrossRef
Continuous application of compressive force induces fusion of osteoclast-like RAW264.7 cells via upregulation of RANK and downregulation of LGR4
Rieko Matsuike, Hideki Tanaka, Kumiko Nakai, Mai Kanda, Maki Nagasaki, Fumiko Murakami, Chika Shibata, Kotoe Mayahara, Akira Nakajima, Natsuko Tanabe, Takayuki Kawato, Masao Maeno, Noriyoshi Shimizu
Life Sciences.2018; 201: 30.     CrossRef
Inhibitory Effects of 2N1HIA (2-(3-(2-Fluoro-4-Methoxyphenyl)-6-Oxo-1(6H)-Pyridazinyl)-N-1H-Indol-5-Ylacetamide) on Osteoclast Differentiation via Suppressing Cathepsin K Expression
Sun-Hee Ahn, Zhihao Chen, Jinkyung Lee, Seok-Woo Lee, Sang Min, Nam Kim, Tae-Hoon Lee
Molecules.2018; 23(12): 3139.     CrossRef
Protocatechuic Acid Attenuates Trabecular Bone Loss in Ovariectomized Mice
Seon-A Jang, Hae Seong Song, Jeong Eun Kwon, Hyun Jin Baek, Hyun Jung Koo, Eun-Hwa Sohn, Sung Ryul Lee, Se Chan Kang
Oxidative Medicine and Cellular Longevity.2018; 2018: 1.     CrossRef
Inhibition of RANKL-stimulated osteoclast differentiation by Schisandra chinensis through down-regulation of NFATc1 and c-fos expression
Eun-Jung Kim, Haesu Lee, Mi Hye Kim, Woong Mo Yang
BMC Complementary and Alternative Medicine.2018;[Epub]     CrossRef
Cyperenoic acid suppresses osteoclast differentiation and delays bone loss in a senile osteoporosis mouse model by inhibiting non-canonical NF-κB pathway
Supatta Chawalitpong, Ratchanaporn Chokchaisiri, Apichart Suksamrarn, Shigeru Katayama, Takakazu Mitani, Soichiro Nakamura, Ahmad AI Athamneh, Patcharee Ritprajak, Asada Leelahavanichkul, Ratchaneevan Aeimlapa, Narattaphol Charoenphandhu, Tanapat Palaga
Scientific Reports.2018;[Epub]     CrossRef
Ferulic acid, a dietary polyphenol suppresses osteoclast differentiation and bone erosion via the inhibition of RANKL dependent NF-κB signalling pathway
Hari Madhuri Doss, Snigdha Samarpita, Ramamoorthi Ganesan, Mahaboobkhan Rasool
Life Sciences.2018; 207: 284.     CrossRef
Reduced miR-144-3p expression in serum and bone mediates osteoporosis pathogenesis by targeting RANK
Chunqing Wang, Hanliang He, Liang Wang, Yu Jiang, Youjia Xu
Biochemistry and Cell Biology.2018; 96(5): 627.     CrossRef
Necrostatin-7 suppresses RANK-NFATc1 signaling and attenuates macrophage to osteoclast differentiation
Hiroaki Fuji, Saori Ohmae, Naruto Noma, Masatoshi Takeiri, Hideto Yasutomi, Kazuya Izumi, Moe Ito, Masayasu Toyomoto, Soichiro Iwaki, Kenji Takemoto, Satoru Seo, Kojiro Taura, Shigeaki Hida, Mineyoshi Aoyama, Yasushi Ishihama, Masatoshi Hagiwara, Norihiko
Biochemical and Biophysical Research Communications.2018; 503(2): 544.     CrossRef
YAP1 is essential for osteoclastogenesis through a TEADs-dependent mechanism
Liming Zhao, Hanfeng Guan, Chao Song, Yuting Wang, Changyu Liu, Cong Cai, Hao Zhu, Hui Liu, Libo Zhao, Jun Xiao
Bone.2018; 110: 177.     CrossRef
c-Src–Dependent and –Independent Functions of Matk in Osteoclasts and Osteoblasts
Jung Ha Kim, Kabsun Kim, Inyoung Kim, Semun Seong, Nacksung Kim
The Journal of Immunology.2018; 200(7): 2455.     CrossRef
Dihydroartemisinin represses osteoclastogenesis of bone marrow macrophages through reduced NFATc1 expression and impaired phosphorylation of IκBα
Shunsuke KOMAKI, Eiko SAKAI, Yutaka FUKUMA, Kazuhisa NISHISHITA, Kuniaki OKAMOTO, Takayuki TSUKUBA
Biomedical Research.2018; 39(4): 169.     CrossRef
Icariin abrogates osteoclast formation through the regulation of the RANKL-mediated TRAF6/NF-κB/ERK signaling pathway in Raw264.7 cells
Buyun Kim, Ki Yong Lee, Byoungduck Park
Phytomedicine.2018; 51: 181.     CrossRef
Desoxyrhapontigenin inhibits RANKL‑induced osteoclast formation and prevents inflammation‑mediated bone loss
Phuong Tran, Dong‑Hwa Park, Okhwa Kim, Seung‑Hae Kwon, Byung‑Sun Min, Jeong‑Hyung Lee
International Journal of Molecular Medicine.2018;[Epub]     CrossRef
Sargassum serratifolium attenuates RANKL-induced osteoclast differentiation and oxidative stress through inhibition of NF-κB and activation of the Nrf2/HO-1 signaling pathway
Hong Jae Kim, Cheol Park, Gi-Young Kim, Eui Kyun Park, You-Jin Jeon, Suhkmann Kim, Hye Jin Hwang, Yung Hyun Choi
BioScience Trends.2018; 12(3): 257.     CrossRef
Bioactive effects of silica nanoparticles on bone cells are size, surface, and composition dependent
Shin-Woo Ha, Manjula Viggeswarapu, Mark M. Habib, George R. Beck
Acta Biomaterialia.2018; 82: 184.     CrossRef
Various roles of heme oxygenase-1 in response of bone marrow macrophages to RANKL and in the early stage of osteoclastogenesis
Urszula Florczyk-Soluch, Ewelina Józefczuk, Jacek Stępniewski, Karolina Bukowska-Strakova, Mateusz Mendel, Monika Viscardi, Witold Norbert Nowak, Alicja Józkowicz, Józef Dulak
Scientific Reports.2018;[Epub]     CrossRef
Targeted delivery of p-coumaric acid encapsulated mannosylated liposomes to the synovial macrophages inhibits osteoclast formation and bone resorption in the rheumatoid arthritis animal model
Manoj Kumar Neog, Mahaboobkhan Rasool
European Journal of Pharmaceutics and Biopharmaceutics.2018; 133: 162.     CrossRef
BCAP promotes osteoclast differentiation through regulation of the p38-dependent CREB signaling pathway
Jung Ha Kim, Kabsun Kim, Inyoung Kim, Semun Seong, Keun-Bae Lee, Nacksung Kim
Bone.2018; 107: 188.     CrossRef
Alveolar Bone Protective Effect of Hiziki Extracts on the Progression of Periodontitis
Don-Gil Lee, Yu-Kyong Shin, Jae-Hee Park, Sang-Yong Park, Eunson Hwang, Jung-Eun Yang, Hae Jo, Ki-Young Kim, Gafurjon T. Mavlonov, Tae-Hoo Yi
Marine Biotechnology.2018; 20(3): 313.     CrossRef
Anti-Osteoporotic Effects of Polysaccharides Isolated from Persimmon Leaves via Osteoclastogenesis Inhibition
Youn-Hwan Hwang, Hyunil Ha, Rajeong Kim, Chang-Won Cho, Young-Ran Song, Hee-Do Hong, Taesoo Kim
Nutrients.2018; 10(7): 901.     CrossRef
Endoplasmic Reticulum–Bound Transcription Factor CREBH Stimulates RANKL-Induced Osteoclastogenesis
Jung Ha Kim, Kabsun Kim, Inyoung Kim, Semun Seong, Kwang-Il Nam, Kyung Keun Kim, Nacksung Kim
The Journal of Immunology.2018; 200(5): 1661.     CrossRef
F4/80 inhibits osteoclast differentiation via downregulation of nuclear factor of activated T cells, cytoplasmic 1
Ju-Hee Kang, Jung-Sun Sim, Ting Zheng, Mijung Yim
Archives of Pharmacal Research.2017; 40(4): 492.     CrossRef
Sophorae Flos extract inhibits RANKL-induced osteoclast differentiation by suppressing the NF-κB/NFATc1 pathway in mouse bone marrow cells
Jeong-Mi Kim, Jung-Han Lee, Guem-San Lee, Eun-mi Noh, Hyun-Kyung Song, Dong Ryun Gu, Seong-Cheol Kim, Seoung Hoon Lee, Kang-Beom Kwon, Young-Rae Lee
BMC Complementary and Alternative Medicine.2017;[Epub]     CrossRef
Effects of Gardeniae Jasminoides on RANKL-induced Osteoclastogenesis and Bone Resorption
You-kyung Choi, Gwi-seo Hwang
The Journal of Internal Korean Medicine.2017; 38(6): 1035.     CrossRef
p‐Coumaric acid, a dietary polyphenol ameliorates inflammation and curtails cartilage and bone erosion in the rheumatoid arthritis rat model
Manoj Kumar Neog, Samuel Joshua Pragasam, Moorthy Krishnan, Mahaboobkhan Rasool
BioFactors.2017; 43(5): 698.     CrossRef
Calcineurin/NFAT signaling pathway mediates titanium particle-induced inflammation and osteoclast formation by inhibiting RANKL and M-CSF in vitro
Yunge Zhang, Peng Jiang, Wenbo Li, Xiangjie Liu, Yang Lu, Zhipeng Huang, Keguan Song
Molecular Medicine Reports.2017; 16(6): 8223.     CrossRef
The effects of downhill and uphill exercise training on osteogenesis-related factors in ovariectomy-induced bone loss
Yun-Seok Kang, Chun-Ho Kim, Jeong-Seok Kim
Journal of Exercise Nutrition & Biochemistry.2017; 21(3): 1.     CrossRef
1,25(OH)2 vitamin D(3) contributes to osteoclast-like trans-differentiation of malignant plasma cells
Paola Cafforio, Stella D’Oronzo, Claudia Felici, Sandra Sigala, Martina Fragni, Francesco Silvestris
Experimental Cell Research.2017; 358(2): 260.     CrossRef
Sappanone A inhibits RANKL-induced osteoclastogenesis in BMMs and prevents inflammation-mediated bone loss
Young-Yeon Choo, Phuong Thao Tran, Byung-Sun Min, Okwha Kim, Hai Dang Nguyen, Seung-Hae Kwon, Jeong-Hyung Lee
International Immunopharmacology.2017; 52: 230.     CrossRef
Human Alternative Macrophages Populate Calcified Areas of Atherosclerotic Lesions and Display Impaired RANKL-Induced Osteoclastic Bone Resorption Activity
Giulia Chinetti-Gbaguidi, Mehdi Daoudi, Mickael Rosa, Manjula Vinod, Loïc Louvet, Corinne Copin, Mélanie Fanchon, Jonathan Vanhoutte, Bruno Derudas, Loic Belloy, Stephan Haulon, Christophe Zawadzki, Sophie Susen, Ziad A. Massy, Jérôme Eeckhoute, Bart Stae
Circulation Research.2017; 121(1): 19.     CrossRef
Sciadopitysin suppresses RANKL-mediated osteoclastogenesis and prevents bone loss in LPS-treated mice
Jinjin Cao, Qiang Lu, Ning Liu, Yu-xin Zhang, Jing Wang, Maolin Zhang, Hong-bing Wang, Wan-chun Sun
International Immunopharmacology.2017; 49: 109.     CrossRef
An Overview of Biomaterials in Periodontology and Implant Dentistry
Young-Dan Cho, Yang-Jo Seol, Yong-Moo Lee, In-Chul Rhyu, Hyun-Mo Ryoo, Young Ku
Advances in Materials Science and Engineering.2017; 2017: 1.     CrossRef
Interleukin-7 Induces Osteoclast Formation via STAT5, Independent of Receptor Activator of NF-kappaB Ligand
Jin-Hee Kim, Ji Hyun Sim, Sunkyung Lee, Min A. Seol, Sang-Kyu Ye, Hyun Mu Shin, Eun Bong Lee, Yun Jong Lee, Yun Jung Choi, Wan-Hee Yoo, Jin Hyun Kim, Wan-Uk Kim, Dong-Sup Lee, Jin-Hong Kim, Insoo Kang, Seong Wook Kang, Hang-Rae Kim
Frontiers in Immunology.2017;[Epub]     CrossRef
TRAF6 Mediates Suppression of Osteoclastogenesis and Prevention of Ovariectomy-Induced Bone Loss by a Novel Prenylflavonoid
Ee Min Tan, Lei Li, Inthrani Raja Indran, Nicholas Chew, Eu-Leong Yong
Journal of Bone and Mineral Research.2017; 32(4): 846.     CrossRef
The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts
Hyunsoo Kim, Matthew C. Walsh, Noriko Takegahara, Sarah A. Middleton, Hong-In Shin, Junhyong Kim, Yongwon Choi
Scientific Reports.2017;[Epub]     CrossRef
Differential intensity‐dependent effects of pulsed electromagnetic fields on RANKL‐induced osteoclast formation, apoptosis, and bone resorbing ability in RAW264.7 cells
Pan Wang, Juan Liu, Yuefan Yang, Mingming Zhai, Xi Shao, Zedong Yan, Xuhui Zhang, Yan Wu, Lu Cao, Bingdong Sui, Erping Luo, Da Jing
Bioelectromagnetics.2017; 38(8): 602.     CrossRef
Natural uranium impairs the differentiation and the resorbing function of osteoclasts
Tatiana Gritsaenko, Valérie Pierrefite-Carle, Thomas Lorivel, Véronique Breuil, Georges F. Carle, Sabine Santucci-Darmanin
Biochimica et Biophysica Acta (BBA) - General Subjects.2017; 1861(4): 715.     CrossRef
Increased levels of sodium chloride directly increase osteoclastic differentiation and resorption in mice and men
L. Wu, B. J. C. Luthringer, F. Feyerabend, Z. Zhang, H. G. Machens, M. Maeda, H. Taipaleenmäki, E. Hesse, R. Willumeit-Römer, A. F. Schilling
Osteoporosis International.2017; 28(11): 3215.     CrossRef
Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells
Chih-Li Lin, Ruijuan Xu, Jae Kyo Yi, Fang Li, Jiang Chen, Evan C. Jones, Jordan B. Slutsky, Liqun Huang, Basil Rigas, Jian Cao, Xiaoming Zhong, Ashley J. Snider, Lina M. Obeid, Yusuf A. Hannun, Cungui Mao
Stem Cell Reports.2017; 9(5): 1488.     CrossRef
Potassium citrate prevents increased osteoclastogenesis resulting from acidic conditions: Implication for the treatment of postmenopausal bone loss
Donatella Granchi, Elena Torreggiani, Annamaria Massa, Renata Caudarella, Gemma Di Pompo, Nicola Baldini, Sakamuri V. Reddy
PLOS ONE.2017; 12(7): e0181230.     CrossRef
ATF3 modulates calcium signaling in osteoclast differentiation and activity by associating with c-Fos and NFATc1 proteins
Byung-Chul Jeong, Jung Ha Kim, Kabsun Kim, Inyoung Kim, Semun Seong, Nacksung Kim
Bone.2017; 95: 33.     CrossRef
Transglutaminase 2 regulates osteoclast differentiation via a Blimp1-dependent pathway
Woo-Shin Kim, Haemin Kim, Eui Man Jeong, Hyung Joon Kim, Zang Hee Lee, In-Gyu Kim, Hong-Hee Kim
Scientific Reports.2017;[Epub]     CrossRef
Genetic modification of ER-Hoxb8 osteoclast precursors using CRISPR/Cas9 as a novel way to allow studies on osteoclast biology
Irene Di Ceglie, Guus G H van den Akker, Giuliana Ascone, Bas ten Harkel, Hans Häcker, Fons A J van de Loo, Marije I Koenders, Peter M van der Kraan, Teun J de Vries, Thomas Vogl, Johannes Roth, Peter L E M van Lent
Journal of Leukocyte Biology.2017; 101(4): 957.     CrossRef
Forced expression of human macrophage colony‐stimulating factor in CD34+ cells promotes monocyte differentiation in vitro and in vivo but blunts osteoclastogenesis in vitro
Carmen P. Montano Almendras, Christian S. Thudium, Henrik Löfvall, Ilana Moscatelli, Axel Schambach, Kim Henriksen, Johan Richter
European Journal of Haematology.2017; 98(5): 517.     CrossRef
STAT5 is a key transcription factor for IL-3-mediated inhibition of RANKL-induced osteoclastogenesis
Jongwon Lee, Semun Seong, Jung Ha Kim, Kabsun Kim, Inyoung Kim, Byung-chul Jeong, Kwang-Il Nam, Kyung Keun Kim, Lothar Hennighausen, Nacksung Kim
Scientific Reports.2016;[Epub]     CrossRef
Biphasic influence of PGE2 on the resorption activity of osteoclast-like cells derived from human peripheral blood monocytes and mouse RAW264.7 cells
Anne-Helen Lutter, Ute Hempel, Ursula Anderer, Peter Dieter
Prostaglandins, Leukotrienes and Essential Fatty Acids.2016; 111: 1.     CrossRef
Melatonin, bone regulation and the ubiquitin-proteasome connection: A review
Jerry Vriend, Russel J. Reiter
Life Sciences.2016; 145: 152.     CrossRef
Nicorandil inhibits osteoclast differentiation in vitro
Futoshi Iwaki, Hitoshi Amano, Kiyoshi Ohura
European Journal of Pharmacology.2016; 793: 14.     CrossRef
Role of CrkII Signaling in RANKL-Induced Osteoclast Differentiation and Function
Jung Ha Kim, Kabsun Kim, Inyoung Kim, Semun Seong, Kwang-Il Nam, Seoung Hoon Lee, Kyung Keun Kim, Nacksung Kim
The Journal of Immunology.2016; 196(3): 1123.     CrossRef
Inhibitory Mechanism of TiO2 Nanotubular Structures in Osteoclast Formation Via Coculture
Seunghan Oh, Su Hyun Jin, Dong Ryun Gu, Seoung Hoon Lee
Korean Journal of Dental Materials.2016; 43(4): 351.     CrossRef
Diarylheptanoid from Curcuma comosa Roxb. suppresses RANKL-induced osteoclast differentiation by decreasing NFATc1 and c-Fos expression via MAPK pathway
Supatta Chawalitpong, Nilubon Sornkaew, Apichart Suksamrarn, Tanapat Palaga
European Journal of Pharmacology.2016; 788: 351.     CrossRef
Enhanced but hypofunctional osteoclastogenesis in an autosomal dominant osteopetrosis type II case carrying a c.1856C>T mutation in CLCN7
Xiang Chen, Kun Zhang, Janet Hock, Chunyu Wang, Xijie Yu
Bone Research.2016;[Epub]     CrossRef
Attenuation of RANKL-induced Osteoclast Formation via p38-mediated NFATc1 Signaling Pathways by Extract ofEuphorbia LathyrisL
Ju-Hee Kang, Hyojung Lim, Ji-Eun Jeong, Mijung Yim
Journal of Bone Metabolism.2016; 23(4): 207.     CrossRef
Amyloid β Peptide Enhances RANKL-Induced Osteoclast Activation through NF-κB, ERK, and Calcium Oscillation Signaling
Shangfu Li, Bu Yang, Dian Teguh, Lin Zhou, Jiake Xu, Limin Rong
International Journal of Molecular Sciences.2016; 17(10): 1683.     CrossRef
United we stand: Adhesion and molecular mechanisms driving cell fusion across species
Francesca Zito, Nadia Lampiasi, Igor Kireev, Roberta Russo
European Journal of Cell Biology.2016; 95(12): 552.     CrossRef
Mitochondria related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK activation
Wei Ming, Gan Lu, Sha Xin, Lu Huanyu, Jiang Yinghao, Lei Xiaoying, Xu Chengming, Ruan Banjun, Wang Li, Lu Zifan
Biochemical and Biophysical Research Communications.2016; 476(4): 412.     CrossRef
DLX3 negatively regulates osteoclastic differentiation through microRNA-124
Na Zhao, Dong Han, Yang Liu, Yue Li, Li Zeng, Yixiang Wang, Hailan Feng
Experimental Cell Research.2016; 341(2): 166.     CrossRef
Thonzonium bromide inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo
Xiang Zhu, Jun J. Gao, Euphemie Landao-Bassonga, Nathan J. Pavlos, An Qin, James H. Steer, Ming H. Zheng, Yang Dong, Tak S. Cheng
Biochemical Pharmacology.2016; 104: 118.     CrossRef
Tatarinan O, a lignin-like compound from the roots of Acorus tatarinowii Schott inhibits osteoclast differentiation through suppressing the expression of c-Fos and NFATc1
Xiaohan Xu, Ning Liu, Yingjian Wang, Lei-chang Pan, Donglin Wu, Qisheng Peng, Maolin Zhang, Hong-bing Wang, Wan-chun Sun
International Immunopharmacology.2016; 34: 212.     CrossRef
RCANs regulate the convergent roles of NFATc1 in bone homeostasis
Jung Ha Kim, Kabsun Kim, Inyoung Kim, Semun Seong, Byung-chul Jeong, Kwang-Il Nam, Kyung Keun Kim, Jeffery D. Molkentin, Nacksung Kim
Scientific Reports.2016;[Epub]     CrossRef
Sinomenine down-regulates TLR4/TRAF6 expression and attenuates lipopolysaccharide-induced osteoclastogenesis and osteolysis
Longgang He, Heng Duan, Xianglian Li, Song Wang, Yueyang Zhang, Linsheng Lei, Jiake Xu, Shuwen Liu, Xiaojuan Li
European Journal of Pharmacology.2016; 779: 66.     CrossRef
Investigation of proteome changes in osteoclastogenesis in low serum culture system using quantitative proteomics
Qi Xiong, Lihai Zhang, Shaohua Zhan, Wei Ge, Peifu Tang
Proteome Science.2016;[Epub]     CrossRef
Development of a High-Throughput Screening Strategy for Upregulators of the OPG/RANKL Ratio with the Potential for Antiosteoporosis Effects
Shiqiang Gong, Xiaowan Han, Xuehong Li, Jun Yang, Xiaobo He, Shuyi Si
SLAS Discovery.2016; 21(7): 738.     CrossRef
Design, synthesis and SARs of novel salicylanilides as potent inhibitors of RANKL-induced osteoclastogenesis and bone resorption
Chun-Liang Chen, Chia-Chung Lee, Fei-Lan Liu, Tsung-Chih Chen, Ahmed Atef Ahmed Ali, Deh-Ming Chang, Hsu-Shan Huang
European Journal of Medicinal Chemistry.2016; 117: 70.     CrossRef
Osteoclasts—Key Players in Skeletal Health and Disease
Deborah Veis Novack, Gabriel Mbalaviele, Siamon Gordon
Microbiology Spectrum.2016;[Epub]     CrossRef
Immunology of Osteoporosis: A Mini-Review
Peter Pietschmann, Diana Mechtcheriakova, Anastasia Meshcheryakova, Ursula Föger-Samwald, Isabella Ellinger
Gerontology.2016; 62(2): 128.     CrossRef
CD137 Regulates NFATc1 Expression in Mouse VSMCs through TRAF6/NF-κB p65 Signaling Pathway
Jinchuan Yan, Yunjie Yin, Wei Zhong, Cuiping Wang, Zhongqun Wang
Mediators of Inflammation.2015; 2015: 1.     CrossRef
Caveolin-1 regulates osteoclast differentiation by suppressing cFms degradation
Yong Deok Lee, Soo-Hyun Yoon, Eunhee Ji, Hong-Hee Kim
Experimental & Molecular Medicine.2015; 47(10): e192.     CrossRef
FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans
Hong Yu, Bethany A. Herbert, Michael Valerio, Leigh Yarborough, Li-Chien Hsu, Kelley M. Argraves
Lipids in Health and Disease.2015;[Epub]     CrossRef
Effect of Spinach Extract on RANKL-Mediated Osteoclast Differentiation
Dong-Gyu Kim, Mi-Hye Kim, Min Jung Kang, Jung Hye Shin
Journal of the Korean Society of Food Science and Nutrition.2015; 44(4): 532.     CrossRef
Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1
Min-Kyoung Song, Zang Hee Lee, Hong-Hee Kim
Experimental & Molecular Medicine.2015; 47(12): e199.     CrossRef
The Multiple Roles of Microrna-223 in Regulating Bone Metabolism
Yong Xie, Lihai Zhang, Yanpan Gao, Wei Ge, Peifu Tang
Molecules.2015; 20(10): 19433.     CrossRef
Dual Role of Cyanidin-3-glucoside on the Differentiation of Bone Cells
K.H. Park, D.R. Gu, H.S. So, K.J. Kim, S.H. Lee
Journal of Dental Research.2015; 94(12): 1676.     CrossRef
Deuxièmes molaires permanentes : origine embryologique, développement et éruption. Rôle de la triade RANK/RANKL/OPG
B. Castaneda, F. Lezot
Revue d'Orthopédie Dento-Faciale.2015; 49(3): 207.     CrossRef
Inhibition of osteoclast differentiation by overexpression of NDRG2 in monocytes
Kyeongah Kang, Sorim Nam, Bomi Kim, Ji Hyun Lim, Young Yang, Myeong-Sok Lee, Jong-Seok Lim
Biochemical and Biophysical Research Communications.2015; 468(4): 611.     CrossRef
NRROS Negatively Regulates Osteoclast Differentiation by Inhibiting RANKL-Mediated NF-κB and Reactive Oxygen Species Pathways
Jung Ha Kim, Kabsun Kim, Inyoung Kim, Semun Seong, Nacksung Kim
Molecules and Cells.2015; 38(10): 904.     CrossRef
Calycosin Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and NF-κB
Gui-Hua Quan, Hongbing Wang, Jinjin Cao, Yuxin Zhang, Donglin Wu, Qisheng Peng, Ning Liu, Wan-Chun Sun
International Journal of Molecular Sciences.2015; 16(12): 29496.     CrossRef