Journal of Bone Metabolism

Review Article

November 4, 2024

Incretin-Based Therapies: A Promising Approach for Modulating Oxidative Stress and Insulin Resistance in Sarcopenia

Raniah I. Alnaser, Fawaz A. Alassaf, Mohammed N. Abed

J Bone Metab. 2024;31(4):251-263.

Background: Recent studies have linked sarcopenia development to the hallmarks of diabetes, oxidative stress, and insulin resistance. The anti-oxidant and insulin sensitivityenhancing effects of incretin-based therapies may provide a promising...

Review Article

November 30, 2024

Clinical Utility of Bone Turnover Markers in Chronic Kidney Disease

Praopilad Srisuwarn, Richard Eastell, Syazrah Salam

J Bone Metab. 2024;31(4):264-278.

Chronic kidney disease (CKD) often leads to mineral and bone disorders (CKD-MBDs), which are nearly universal in patients undergoing dialysis. CKD-MBD includes abnormal calcium-phosphate metabolism, vascular and soft tissue calcification,...

Original Article

November 30, 2024

María Lorena Brance, Fernando Daniel Saraví, Muriel M. Henríquez, et al.

J Bone Metab. 2024;31(4):279-289.

Background: There are age- and sex-related increases in the prevalence of osteoporosis. Bone densitometry based on dual energy X-ray absorptiometry (DXA) is the gold standard for the assessment of bone...

Original Article

November 4, 2024

Zoledronate Therapy in Osteogenesis Imperfecta: Perspectives in Indonesia Tertiary Hospital

Tri Wahyu Martanto, Aliefio Japamadisaw, Dian Nurhayati, et al.

J Bone Metab. 2024;31(4):290-295.

Background: Osteogenesis imperfecta (OI) is a rare disease with an estimated incidence of between 1/25,000 and 1/10,000 globally. The main treatment for OI is the administration of bisphosphonate drugs. Research...

Original Article

November 30, 2024

Discriminatory Accuracy of Fracture Risk Assessment Tool in Asian Populations: A Systematic Review and Meta-Analysis

Dheeraj Jha, Manju Chandran, Namki Hong, et al.

J Bone Metab. 2024;31(4):296-315.

Background: This review explores the discriminative ability of fracture risk assessment tool (FRAX) in major osteoporotic fracture (MOF) and hip fracture (HF) risk prediction and the densitometric diagnosis of osteoporosis...

Original Article

November 30, 2024

Physical Performance Level and Patient-Reported Outcomes in Female Patients with Distal Radius Fracture

Byung Hun Oh, Rawdhah Kamil Kalantan, Jae Kwang Kim, et al.

J Bone Metab. 2024;31(4):316-325.

Background: This study aimed to evaluate the influence of physical performance level on patient-reported outcomes after surgery for distal radius fractures (DRF). Methods: We retrospectively reviewed 157 women with DRF who...

Original Article

November 30, 2024

Relationships among Physical Activity Bone Mineral Density and Body Composition in Obese and Athletes

Dutsadee Suttho, Sudarat Apibantaweesakul, Jatesupa Soponputthaporn, et al.

J Bone Metab. 2024;31(4):326-334.

Background: Osteoporosis is a significant global public health issue, increasingly affecting younger individuals and placing substantial economic burdens on society. Risk factors vary, with non-modifiable ones like age and ethnicity,...

Case Report

November 30, 2024

Platelet Count Normalization Following Romosozumab Treatment for Osteoporosis in Patient with Immune Thrombocytopenic Purpura: A Case Report and Literature Review

Kyunghun Sung, Jeonghoon Ha

J Bone Metab. 2024;31(4):335-339.

Romosozumab, which is approved for the treatment of osteoporosis, has a dual-action mechanism that promotes bone formation and inhibits bone resorption. However, its association with an increased risk of major...

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